SORL1 anticorps (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing) (AA 2159-2214)

Details for Product anti-SORL1 Antibody No. ABIN1724683
Antigène
  • SORL1
  • C11orf32
  • LR11
  • LRP9
  • SORLA
  • SorLA-1
  • gp250
  • SorLA
  • 2900010L19Rik
  • AI596264
  • AW261561
  • mSorLA
  • Lr11
  • RGD619914
  • sortilin related receptor 1
  • sortilin-related receptor
  • sortilin-related receptor, L(DLR class) A repeats containing
  • sortilin-related receptor, L(DLR class) A repeats-containing
  • sortilin-related receptor, LDLR class A repeats-containing
  • sorl1
  • LOC582560
  • SORL1
  • Sorl1
Épitope
AA 2159-2214
16
12
6
4
3
2
1
1
1
Reactivité
Humain
74
39
22
4
3
1
1
1
1
1
1
Hôte
Souris
46
26
17
3
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp SORL1 est non-conjugé
6
6
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
62
57
25
13
9
9
5
1
1
1
1
Options
Immunogène Purified recombinant fragment of SORL1 (aa2159-2214) expressed in E. Coli.
Clone 7D7B11
Isotype IgG1
Plasmids, Primers & others Plasmids, Primers & others SORL1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation SORL1 (SORL1 Antibody Extrait)
Sujet SORL1 (sortilin-related receptor, L A repeats containing) also known as sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. The gene encoding for the protein maps to chromosome 8p23.1. SorLA is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.
ID gène 6653
HGNC 6653
Pathways Smooth Muscle Cell Migration
Indications d'application ELISA: 1:10000, WB: 1:500 - 1:2000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C,-20 °C
Stockage commentaire 4°C, -20°C for long term storage
Images (Fournisseur)
Western Blotting (WB) image for anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 2159-2214) antibody (ABIN1724683) anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 2159-2214) antibody
Produit citée dans: Shah, Yu: "sorLA: sorting out APP." dans: Molecular interventions, Vol. 6, Issue 2, pp. 74-6, 58, 2006 (PubMed).

Gabrielsson, Olofsson, Sjögren, Jernås, Elander, Lönn, Rudemo, Carlsson: "Evaluation of reference genes for studies of gene expression in human adipose tissue." dans: Obesity research, Vol. 13, Issue 4, pp. 649-52, 2005 (PubMed).

Scherzer, Offe, Gearing, Rees, Fang, Heilman, Schaller, Bujo, Levey, Lah: "Loss of apolipoprotein E receptor LR11 in Alzheimer disease." dans: Archives of neurology, Vol. 61, Issue 8, pp. 1200-5, 2004 (PubMed).

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