SORL1 anticorps (AA 2159-2214)

N° du produit ABIN1724683

Détail du produit anti-SORL1 anticorps

Antigène: SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))

Épitope: AA 2159-2214

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SORL1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: purified

Immunogène: Purified recombinant fragment of SORL1 (aa2159-2214) expressed in E. coli.

Clone: 7D7B11

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-SORL1 (ABIN1724683)

Shah, Yu: "sorLA: sorting out APP." dans: Molecular interventions, Vol. 6, Issue 2, pp. 74-6, 58, (2006) (PubMed).

Gabrielsson, Olofsson, Sjögren, Jernås, Elander, Lönn, Rudemo, Carlsson: "Evaluation of reference genes for studies of gene expression in human adipose tissue." dans: Obesity research, Vol. 13, Issue 4, pp. 649-52, (2005) (PubMed).

Scherzer, Offe, Gearing, Rees, Fang, Heilman, Schaller, Bujo, Levey, Lah: "Loss of apolipoprotein E receptor LR11 in Alzheimer disease." dans: Archives of neurology, Vol. 61, Issue 8, pp. 1200-5, (2004) (PubMed).

Détails sur SORL1

Antigène: SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))

Autre désignation: SORL1 (SORL1 Produits)

Synonymes: anticorps SORL1, anticorps C11orf32, anticorps LR11, anticorps LRP9, anticorps SORLA, anticorps SorLA-1, anticorps gp250, anticorps SorLA, anticorps 2900010L19Rik, anticorps AI596264, anticorps AW261561, anticorps mSorLA, anticorps Lr11, anticorps RGD619914, anticorps sortilin related receptor 1, anticorps sortilin-related receptor, anticorps sortilin-related receptor, L(DLR class) A repeats containing, anticorps sortilin-related receptor, L(DLR class) A repeats-containing, anticorps sortilin-related receptor, LDLR class A repeats-containing, anticorps sorl1, anticorps LOC582560, anticorps SORL1, anticorps Sorl1

Sujet:

Description: SORL1 (sortilin-related receptor, L A repeats containing) also known as sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. The gene encoding for the protein maps to chromosome 8p23.1. SorLA is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.

Aliases: SORL1

ID gène: 6653

HGNC: 6653

Pathways: Smooth Muscle Cell Migration