SRC anticorps (V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian)) (AA 10-193)

Details for Product anti-SRC Antibody No. ABIN1724696, Fournisseur: Connectez-vous pour afficher
Antigène
  • AW259666
  • pp60c-src
  • C-src1
  • CG7524
  • D-Src64B
  • D-src
  • DSRC64
  • DSrc
  • DSrc64
  • DSrc64B
  • Dm SRC1
  • DmHD-358
  • Dmel\CG7524
  • Dsrc
  • Dsrc64
  • Dsrc64B
  • HD-358
  • MRE5
  • SRC 64B
  • Src
  • Src1
  • Src64
  • c-src
  • dSrc
  • dsrc
  • src
  • src1
  • src64
  • src64B
  • src64b
  • ASV
  • SRC1
  • c-SRC
  • p60-Src
  • c-Src
  • PP60C-SCR
  • SDR
  • SRC proto-oncogene, non-receptor tyrosine kinase
  • uncharacterized LOC5574802
  • proto-oncogene tyrosine-protein kinase src
  • Rous sarcoma oncogene
  • Src oncogene at 64B
  • SRC
  • LOC5574802
  • CpipJ_CPIJ010659
  • Src
  • Src64B
Épitope
AA 10-193
46
36
36
34
28
20
19
16
14
12
11
11
7
7
7
6
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
461
265
215
26
15
14
13
10
8
5
5
4
4
3
2
1
1
1
1
Hôte
Souris
410
72
1
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp SRC est non-conjugé
20
19
15
15
14
13
3
3
2
2
2
2
2
2
2
2
2
2
1
Application
ELISA, Western Blotting (WB)
419
239
201
57
53
30
27
22
20
14
12
5
3
3
1
Options
Fournisseur
Connectez-vous pour afficher
N° du produit (Fournisseur)
Connectez-vous pour afficher
Immunogène Purified recombinant fragment of SRC (aa10-193) expressed in E. Coli.
Clone 4F1E8
Isotype IgG2b
Plasmids, Primers & others Plasmids, Primers & others SRC products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation SRC (SRC Antibody Extrait)
Sujet SRC: v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian). This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
ID gène 6714
HGNC 6714
Pathways Signalistation JAK/STAT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Indications d'application ELISA: 1:10000, WB: 1:500 - 1:2000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C,-20 °C
Stockage commentaire 4°C, -20°C for long term storage
Images (Fournisseur)
Western Blotting (WB) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 10-193) antibody (ABIN1724696) anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 10-193) antibody
Produit citée dans: Li, Aurandt, Jürgensen, Jürgense, Rao, Guan: "FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5." dans: Journal of cell science, Vol. 119, Issue Pt 1, pp. 47-55, 2005 (PubMed).

Summy, Trevino, Baker, Gallick: "c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells through activation of phosphatidyl inositol-3 kinase and p38 MAPK." dans: Pancreas, Vol. 31, Issue 3, pp. 263-74, 2005 (PubMed).

Zheng, Yano, Matsumori, Nakataki, Muguruma, Yoshizumi, Sone et al.: "SRC tyrosine kinase inhibitor, m475271, suppresses subcutaneous growth and production of lung metastasis via inhibition of proliferation, invasion, and vascularization of human lung adenocarcinoma ..." dans: Clinical & experimental metastasis, Vol. 22, Issue 3, pp. 195-204, 2005 (PubMed).

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