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Integrin beta 4 anticorps (AA 1619-1822)

ITGB4 Reactivité: Humain WB, IHC, FACS, ELISA Hôte: Souris Monoclonal 10B10D5 unconjugated
N° du produit ABIN1724805
  • Antigène Voir toutes Integrin beta 4 (ITGB4) Anticorps
    Integrin beta 4 (ITGB4)
    Épitope
    • 16
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1619-1822
    Reactivité
    • 83
    • 30
    • 26
    • 3
    • 3
    Humain
    Hôte
    • 56
    • 38
    • 12
    • 2
    Souris
    Clonalité
    • 58
    • 50
    Monoclonal
    Conjugué
    • 57
    • 9
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Integrin beta 4 est non-conjugé
    Application
    • 54
    • 46
    • 31
    • 28
    • 21
    • 17
    • 15
    • 13
    • 13
    • 9
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. coli.
    Clone
    10B10D5
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Liu, Qin, Liu, Xiang: "Downregulation of integrin β4 decreases the ability of airway epithelial cells to present antigens." dans: PLoS ONE, Vol. 7, Issue 4, pp. e32060, (2012) (PubMed).

  • Antigène
    Integrin beta 4 (ITGB4)
    Autre désignation
    ITGB4 (ITGB4 Produits)
    Synonymes
    anticorps AA407042, anticorps C230078O20, anticorps CD104, anticorps integrin subunit beta 4, anticorps integrin beta 4, anticorps ITGB4, anticorps Itgb4
    Sujet

    Description: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. , , ,

    Aliases: CD104

    Poids moléculaire
    202 kDa
    ID gène
    3691
    HGNC
    3691
    Pathways
    Integrin Complex
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