Paired Box 3 anticorps (AA 142-203)

N° du produit ABIN1724817

Détail du produit anti-Paired Box 3 anticorps

Antigène: Paired Box 3 (PAX3)

Épitope: AA 142-203

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Paired Box 3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogène: Purified recombinant fragment of human PAX3 (AA: 142-203) expressed in E. coli.

Clone: 7D8G7

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-Paired Box 3 (ABIN1724817)

Dong, Li, Cao, Liu, Pier, Chen, Xu, Chen, Wang, Cui: "FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription." dans: Cell death and differentiation, Vol. 19, Issue 4, pp. 616-22, (2012) (PubMed).

Détails sur Paired Box 3

Antigène: Paired Box 3 (PAX3)

Autre désignation: PAX3 (PAX3 Produits)

Synonymes: anticorps PAX3, anticorps cdhs, anticorps hup2, anticorps pax-3, anticorps ws1, anticorps xpax3, anticorps Pax3, anticorps pax3, anticorps pax3b, anticorps xPax3-B, anticorps CDHS, anticorps HUP2, anticorps WS1, anticorps WS3, anticorps Pax-3, anticorps Sp, anticorps splotch, anticorps zgc:92547, anticorps paired box 3, anticorps paired box 3 L homeolog, anticorps paired box 3a, anticorps PAX3, anticorps pax3, anticorps pax3.L, anticorps Pax3, anticorps pax3a

Sujet:

Description: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. , ,

Aliases: WS1, WS3, CDHS, HUP2

Poids moléculaire: 53 kDa

ID gène: 5077

HGNC: 5077

Pathways: Sensory Perception of Sound, Tube Formation