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PRKAG1 anticorps (AA 230-331)

PRKAG1 Reactivité: Humain WB, ELISA, IHC Hôte: Souris Monoclonal 4A1G9 unconjugated
N° du produit ABIN1724935
  • Antigène Voir toutes PRKAG1 Anticorps
    PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
    Épitope
    • 9
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 230-331
    Reactivité
    • 49
    • 24
    • 7
    Humain
    Hôte
    • 47
    • 2
    Souris
    Clonalité
    • 46
    • 3
    Monoclonal
    Conjugué
    • 24
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PRKAG1 est non-conjugé
    Application
    • 38
    • 30
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human PRKAG1 (AA: 230-331) expressed in E. coli.
    Clone
    4A1G9
    Isotype
    IgG1
    Top Product
    Discover our top product PRKAG1 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Zaha, Young: "AMP-activated protein kinase regulation and biological actions in the heart." dans: Circulation research, Vol. 111, Issue 6, pp. 800-14, (2012) (PubMed).

    Oliveira, Zhang, Solis, Isackson, Bellahcene, Yavari, Pinter, Davies, Ge, Ashrafian, Walker, Carling, Watkins, Casadei, Redwood: "AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes." dans: Circulation research, Vol. 110, Issue 9, pp. 1192-201, (2012) (PubMed).

  • Antigène
    PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
    Autre désignation
    PRKAG1 (PRKAG1 Produits)
    Synonymes
    anticorps MGC68503, anticorps zgc:63896, anticorps wu:fa94d09, anticorps wu:fd12h04, anticorps AMPKG, anticorps Prkaac, anticorps Prkga1, anticorps AA571379, anticorps BB036179, anticorps protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog, anticorps protein kinase, AMP-activated, gamma 1 non-catalytic subunit, anticorps protein kinase AMP-activated non-catalytic subunit gamma 1, anticorps prkag1.S, anticorps prkag1, anticorps PRKAG1, anticorps Prkag1
    Sujet

    Description: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. ,

    Aliases: AMPKG

    Poids moléculaire
    37.6 kDa
    ID gène
    5571
    HGNC
    5571
    Pathways
    AMPK Signaling, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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