ADAMTS4 anticorps
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- Antigène Voir toutes ADAMTS4 Anticorps
- ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ADAMTS4 est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- Reacts with human ADAMTS4
- Réactivité croisée (Details)
- BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Purification
- Antigen affinity purified
- Immunogène
- Synthetic 15 amino acid peptide from Disintegrin-like domain of human ADAMTS4. Percent identity with other species by BLAST analysis: Human (100%), Orangutan (100%), Gibbon (100%), Monkey (100%), Marmoset (100%), Mouse (100%), Hamster (100%)
- Isotype
- IgG
- Top Product
- Discover our top product ADAMTS4 Anticorps primaire
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- Indications d'application
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Working dilution: IHC - P (2 μg/mL
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, Sodium azide 0.1 %
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-80 °C
- Stockage commentaire
- Long term: -70°C, Short term: +4°C
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- Antigène
- ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
- Autre désignation
- ADAMTS4 (ADAMTS4 Produits)
- Synonymes
- anticorps 3830423K05, anticorps ADAM-TS4, anticorps ADAMTS-2, anticorps ADMP-1, anticorps mKIAA0688, anticorps ADAMTS-4, anticorps ADAMTS4, anticorps a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4, anticorps ADAM metallopeptidase with thrombospondin type 1 motif 4, anticorps ADAM metallopeptidase with thrombospondin type 1 motif, 4, anticorps Adamts4, anticorps ADAMTS4
- Sujet
- Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
- UniProt
- O75173
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