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CYP3A4 anticorps
CYP3A4
Reactivité: Humain
WB, ELISA, IHC, FACS, IF/ICC
Hôte: Souris
Monoclonal
unconjugated
N° du produit ABIN1846452
Détail du produit anti-CYP3A4 anticorps
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Antigène
Voir toutes CYP3A4 Anticorps
CYP3A4
(Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
Reactivité
Toutes les réactivités sur CYP3A4 Anticorps
Humain
Hôte
Toutes les hôtes sur CYP3A4 Anticorps
Souris
Clonalité
Toutes les clonalités sur CYP3A4 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CYP3A4 Anticorps
Cet anticorp CYP3A4 est non-conjugé
Application
Tous les applications à travers CYP3A4 Anticorps.
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)
Purification
Purified antibody
Immunogène
Purified recombinant fragment of human CYP3A4 expressed in E. Coli.
Isotype
IgG1
Top Product
Discover our top product CYP3A4 Anticorps primaire
Alternatives
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anti-Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) (AA 18-120) antibody
CYP3A4
Reactivité: Humain, Souris, Rat
WB, FACS, IF (p), IHC (p), ICC, IF (cc), IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Détails sur CYP3A4
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Antigène
CYP3A4
(Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
Autre désignation
CYP3A4 (CYP3A4 Produits )
Synonymes
anticorps CP33, anticorps CP34, anticorps CYP3A, anticorps CYP3A3, anticorps CYPIIIA3, anticorps CYPIIIA4, anticorps HLP, anticorps NF-25, anticorps P450C3, anticorps P450PCN1, anticorps MGC108372, anticorps CYP3A80, anticorps CYP3A4, anticorps CYP3A21, anticorps CYPIIIA21, anticorps CYP3A12, anticorps cytochrome P450 family 3 subfamily A member 4, anticorps cytochrome P450 family 3 subfamily A member 43, anticorps cytochrome P450 3A4, anticorps cytochrome P450, subfamily IIIA, polypeptide 4, anticorps cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, anticorps cytochrome P450, family 3, subfamily A, polypeptide 4, anticorps CYP3A4, anticorps CYP3A43, anticorps PTRG_01782, anticorps PTRG_06060, anticorps cyp3a4
Sujet
This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist, however, it is now thought that this sequence represents a transcript variant of CYP3A4.
Poids moléculaire
57.3 kDa
ID gène
1576
UniProt
P08684
Pathways
Steroid Hormone Biosynthesis
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