IL-6 Receptor anticorps (Internal Region)

N° du produit ABIN185570

Détail du produit anti-IL-6 Receptor anticorps

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-6 Receptor est non-conjugé

Application: ELISA

Fonction: IL6R / CD126 (isoform 1)

Séquence: DNTSSHNRPD ARD

Specificité: This antibody is expected to recognise isoform 1 only (NP_000556.1)

Homologie: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Classe de qualité: Recent

Immunogène: Peptide with sequence C-DNTSSHNRPDARD, from the internal region of the protein sequence according to NP_000556.1.

Isotype: IgG

Information d'application

Indications d'application:

DS WB Results: Preliminary experiments gave an approx 26-28 kDa band in Human Bone Marrow and Tonsil lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 51.5 kDa according to NP_000556.1. The 26-28 kDa band was successfully blocked by incubation with the immunizing peptide. Have any further splice variants/modified forms been reported?

Peptide ELISA: antibody detection limit dilution 1:8000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Détails sur IL-6 Receptor

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Autre désignation: IL6R / CD126 (IL6R Produits)

Synonymes: anticorps IL6R, anticorps il-6ra, anticorps CD126, anticorps IL-6R-1, anticorps IL-6RA, anticorps IL6Q, anticorps IL6RA, anticorps IL6RQ, anticorps gp80, anticorps IL6R1, anticorps Il6ra, anticorps IL-6Ralpha, anticorps IL-6R, anticorps Il6r, anticorps interleukin 6 receptor, anticorps interleukin 6 receptor, alpha, anticorps IL6R, anticorps il6r, anticorps Il6r, anticorps Il6ra

Sujet: IL6R, interleukin 6 receptor , HGNC:6019, CD126, IL-6R-1, IL-6R-alpha, IL6RA, MGC104991 , CD126 antigen, interleukin 6 receptor alpha subunit

ID gène: 3570

NCBI Accession: NP_000556

Pathways: Signalistation JAK/STAT, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints