NR1I2 anticorps (AA 205-390)

N° du produit ABIN1860380

Détail du produit anti-NR1I2 anticorps

Antigène: NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))

Épitope: AA 205-390

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR1I2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Fonction: Polyclonal Antibody to Pregnane X Receptor (PXR)

Specificité: The antibody is a rabbit polyclonal antibody raised against PXR. It has been selected for its ability to recognize PXR in immunohistochemical staining and western blotting.

Réactivité croisée: Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogène: Recombinant Pregnane X Receptor (PXR) corresdonding to Tyr205-Gly390 with N-terminal His and GST Tag

Isotype: IgG

Information d'application

Indications d'application:

Western blotting: 0.5-2 μg/mL

Immunohistochemistry: 5-20 μg/mL

Immunocytochemistry: 5-20 μg/mL

Optimal working dilutions must be determined by end user.

Commentaires:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Date de péremption: 24 months

Références pour anticorps anti-NR1I2 (ABIN1860380)

Huang, Mukherjee, DesMarais, Albanese, Rafti, Draghi Ii, Maher, Khanna, Mani, Matson: "Targeting the PXR-TLR4 signaling pathway to reduce intestinal inflammation in an experimental model of necrotizing enterocolitis." dans: Pediatric research, Vol. 83, Issue 5, pp. 1031-1040, (2018) (PubMed).

Détails sur NR1I2

Antigène: NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))

Autre désignation: Pregnane X Receptor (NR1I2 Produits)

Synonymes: anticorps BXR, anticorps ONR1, anticorps PAR, anticorps PAR1, anticorps PAR2, anticorps PARq, anticorps PRR, anticorps PXR, anticorps SAR, anticorps SXR, anticorps PXR.1, anticorps PXR.2, anticorps PXR1, anticorps mPXR, anticorps bxr, anticorps nr1i2, anticorps onr1, anticorps xonr1, anticorps nuclear receptor subfamily 1 group I member 2, anticorps nuclear receptor subfamily 1, group I, member 2, anticorps nuclear receptor subfamily 1 group I member 2 S homeolog, anticorps NR1I2, anticorps Nr1i2, anticorps nr1i2.S, anticorps nr1i2

Sujet: NR1I2, SAR, PAR1, PAR2, PRR, BXR, ONR1, PAR, PARq, SXR, Nuclear Receptor Subfamily 1,Group I,Member 2, Steroid and xenobiotic receptor, Pregnane X receptor

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway