CASQ2 anticorps (AA 79-107)

N° du produit ABIN1881138

Détail du produit anti-CASQ2 anticorps

Antigène: CASQ2 (Calsequestrin 2 (CASQ2))

Épitope: AA 79-107

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CASQ2 est non-conjugé

Application: Western Blotting (WB)

Homologie: Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CASQ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the Central region of human CASQ2.

Clone: RB41817

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CASQ2 (ABIN1881138)

Kirchhefer, Wehrmeister, Postma, Pohlentz, Mormann, Kucerova, Müller, Schmitz, Schulze-Bahr, Wilde, Neumann: "The human CASQ2 mutation K206N is associated with hyperglycosylation and altered cellular calcium handling." dans: Journal of molecular and cellular cardiology, Vol. 49, Issue 1, pp. 95-105, (2010) (PubMed).

Wei, Hanna, Beard, Dulhunty: "Unique isoform-specific properties of calsequestrin in the heart and skeletal muscle." dans: Cell calcium, Vol. 45, Issue 5, pp. 474-84, (2009) (PubMed).

Détails sur CASQ2

Antigène: CASQ2 (Calsequestrin 2 (CASQ2))

Autre désignation: CASQ2 (CASQ2 Produits)

Synonymes: anticorps CASQ2, anticorps DKFZp468D075, anticorps AA033488, anticorps AW146219, anticorps ESTM52, anticorps cCSQ, anticorps PDIB2, anticorps cardCSQ, anticorps CASQ1, anticorps CAL, anticorps calsequestrin 2, anticorps CASQ2, anticorps Casq2

Sujet: The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq].

Poids moléculaire: 46436

NCBI Accession: NP_001223

UniProt: O14958

Pathways: Negative Regulation of Transporter Activity