CDK14 anticorps (N-Term)

N° du produit ABIN1881191

Détail du produit anti-CDK14 anticorps

Antigène: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Épitope: AA 45-72, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK14 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Cdk14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-72 amino acids from the N-terminal region of mouse Cdk14.

Clone: RB40562

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CDK14 (ABIN1881191)

Quina, Wang, Ng, Turner: "Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 45, pp. 14309-22, (2009) (PubMed).

Jiang, Gao, Yang, Zhu, Chen: "Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1." dans: FEBS letters, Vol. 583, Issue 13, pp. 2171-8, (2009) (PubMed).

Détails sur CDK14

Antigène: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Autre désignation: Cdk14 (CDK14 Produits)

Synonymes: anticorps PFTK1, anticorps PFTAIRE1, anticorps Pftk1, anticorps mKIAA0834, anticorps pftaire1, anticorps pftk1, anticorps cyclin dependent kinase 14, anticorps cyclin-dependent kinase 14, anticorps cyclin-dependent kinase 14 L homeolog, anticorps CDK14, anticorps Cdk14, anticorps cdk14.L

Sujet: Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport (By similarity).

Poids moléculaire: 52996

NCBI Accession: NP_035204

UniProt: O35495