CNBP anticorps (AA 91-118)

N° du produit ABIN1881216

Détail du produit anti-CNBP anticorps

Antigène: CNBP (CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP))

Épitope: AA 91-118

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, C, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CNBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-118 amino acids from the Central region of human CNBP.

Clone: RB43101

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CNBP (ABIN1881216)

Catalli, Morgante, Iraci, Rinaldi, Botta, Novelli: "Validation of sensitivity and specificity of tetraplet-primed PCR (TP-PCR) in the molecular diagnosis of myotonic dystrophy type 2 (DM2)." dans: The Journal of molecular diagnostics : JMD, Vol. 12, Issue 5, pp. 601-6, (2010) (PubMed).

Massa, Panico, Caldarola, Fusco, Sabatelli, Terracciano, Botta, Novelli, Bernardi, Loreni: "The myotonic dystrophy type 2 (DM2) gene product zinc finger protein 9 (ZNF9) is associated with sarcomeres and normally localized in DM2 patients' muscles." dans: Neuropathology and applied neurobiology, Vol. 36, Issue 4, pp. 275-84, (2010) (PubMed).

Auvinen, Suominen, Hannonen, Bachinski, Krahe, Udd: "Myotonic dystrophy type 2 found in two of sixty-three persons diagnosed as having fibromyalgia." dans: Arthritis and rheumatism, Vol. 58, Issue 11, pp. 3627-31, (2008) (PubMed).

Panayiotopoulos, Scarpalezos: "Dystrophia myotonica. Peripheral nerve involvement and pathogenetic implications." dans: Journal of the neurological sciences, Vol. 27, Issue 1, pp. 1-16, (1976) (PubMed).

Détails sur CNBP

Antigène: CNBP (CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP))

Autre désignation: CNBP (CNBP Produits)

Synonymes: anticorps An07g10270, anticorps ZNF9, anticorps CNBP1, anticorps DM2, anticorps PROMM, anticorps RNF163, anticorps ZCCHC22, anticorps Cnbp1, anticorps Znf9, anticorps cnbp1, anticorps cnbpa, anticorps dm2, anticorps promm, anticorps rnf163, anticorps xcnbp, anticorps zcchc22, anticorps znf9, anticorps AA408710, anticorps cellular nucleic acid-binding protein, anticorps zinc finger protein Byr3, anticorps CCHC-type zinc finger nucleic acid binding protein, anticorps CCHC-type zinc finger, nucleic acid binding protein, anticorps CCHC-type zinc finger nucleic acid binding protein L homeolog, anticorps cellular nucleic acid binding protein, anticorps ANI_1_1316064, anticorps AOR_1_1792194, anticorps PTRG_02341, anticorps PTRG_04792, anticorps SJAG_02043, anticorps VDBG_00279, anticorps VDBG_00590, anticorps CNBP, anticorps Cnbp, anticorps cnbp.L

Sujet: This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 19463

NCBI Accession: NP_001120664, NP_001120665, NP_001120666, NP_001120668, NP_003409

UniProt: P62633