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GTPBP3 anticorps (AA 293-320)

GTPBP3 Reactivité: Humain WB Hôte: Lapin Polyclonal RB40710 unconjugated
N° du produit ABIN1881398
  • Antigène Voir toutes GTPBP3 Anticorps
    GTPBP3 (GTP Binding Protein 3 (Mitochondrial) (GTPBP3))
    Épitope
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 293-320
    Reactivité
    • 13
    • 1
    • 1
    Humain
    Hôte
    • 12
    • 1
    Lapin
    Clonalité
    • 13
    Polyclonal
    Conjugué
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GTPBP3 est non-conjugé
    Application
    • 12
    • 10
    • 4
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This GTPBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-320 amino acids from the Central region of human GTPBP3.
    Clone
    RB40710
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GTPBP3 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Reiling, van Vliet-Ostaptchouk, van t Riet, van Haeften, Arp, Hansen, Kremer, Groenewoud, van Hove, Romijn, Smit, Nijpels, Heine, Uitterlinden, Pedersen, Slagboom, Maassen, Hofker, t Hart, Dekker: "Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study." dans: European journal of human genetics : EJHG, Vol. 17, Issue 8, pp. 1056-62, (2009) (PubMed).

    Villarroya, Prado, Esteve, Soriano, Aguado, Pérez-Martínez, Martínez-Ferrandis, Yim, Victor, Cebolla, Montaner, Knecht, Armengod: "Characterization of human GTPBP3, a GTP-binding protein involved in mitochondrial tRNA modification." dans: Molecular and cellular biology, Vol. 28, Issue 24, pp. 7514-31, (2008) (PubMed).

    Bykhovskaya, Mengesha, Wang, Yang, Estivill, Shohat, Fischel-Ghodsian: "Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3." dans: Molecular genetics and metabolism, Vol. 83, Issue 3, pp. 199-206, (2004) (PubMed).

    Li, Guan: "Identification and characterization of mouse GTPBP3 gene encoding a mitochondrial GTP-binding protein involved in tRNA modification." dans: Biochemical and biophysical research communications, Vol. 312, Issue 3, pp. 747-54, (2003) (PubMed).

    Li, Guan: "A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation." dans: Molecular and cellular biology, Vol. 22, Issue 21, pp. 7701-11, (2002) (PubMed).

  • Antigène
    GTPBP3 (GTP Binding Protein 3 (Mitochondrial) (GTPBP3))
    Autre désignation
    GTPBP3 (GTPBP3 Produits)
    Synonymes
    anticorps GTPBP3, anticorps zgc:112394, anticorps 2410009F13Rik, anticorps AI607903, anticorps GTPBG3, anticorps MSS1, anticorps MTGP1, anticorps THDF1, anticorps GTP binding protein 3, mitochondrial, anticorps GTP binding protein 3, anticorps GTPBP3, anticorps Gtpbp3, anticorps gtpbp3
    Sujet
    This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.
    Poids moléculaire
    52058
    NCBI Accession
    NP_001122327, NP_001182351, NP_116009, NP_598399
    UniProt
    Q969Y2
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