This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This DANRE hey2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 amino acids from the C-terminal region of DANRE hey2.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Winkler, Elmasri, Klamt, Volff, Gessler: "Characterization of hey bHLH genes in teleost fish." dans: Development genes and evolution, Vol. 213, Issue 11, pp. 541-53, (2003) (PubMed).
Zhong, Childs, Leu, Fishman: "Gridlock signalling pathway fashions the first embryonic artery." dans: Nature, Vol. 414, Issue 6860, pp. 216-20, (2001) (PubMed).
Zhong, Rosenberg, Mohideen, Weinstein, Fishman: "gridlock, an HLH gene required for assembly of the aorta in zebrafish." dans: Science (New York, N.Y.), Vol. 287, Issue 5459, pp. 1820-4, (2000) (PubMed).
Antigène
HEY2
(Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))
anticorps CHF1, anticorps GRIDLOCK, anticorps GRL, anticorps HERP1, anticorps HESR2, anticorps HRT2, anticorps bHLHb32, anticorps Herp1, anticorps Hrt2, anticorps hesr2, anticorps grl, anticorps zgc:136746, anticorps hes related family bHLH transcription factor with YRPW motif 2, anticorps hairy/enhancer-of-split related with YRPW motif 2, anticorps hes-related family bHLH transcription factor with YRPW motif 2, anticorps HEY2, anticorps Hey2, anticorps hey2
Sujet
Transcriptional repressor (By similarity). Downstream effector of Notch signaling which regulates cell fate choice in angioblasts. Represses the venous cell fate, thereby promoting the arterial cell fate and aorta formation.