HIST2H2BE anticorps (N-Term)

N° du produit ABIN1881418

Détail du produit anti-HIST2H2BE anticorps

Antigène: HIST2H2BE (Histone H2B Type 2-E (HIST2H2BE))

Épitope: AA 12-40, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIST2H2BE est non-conjugé

Application: Western Blotting (WB)

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HIST2H2BE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human HIST2H2BE.

Clone: RB41930

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-HIST2H2BE (ABIN1881418)

Kim, Guermah, McGinty, Lee, Tang, Milne, Shilatifard, Muir, Roeder: "RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells." dans: Cell, Vol. 137, Issue 3, pp. 459-71, (2009) (PubMed).

Pankratova, Manuĭlova, Stepchenko: "[Role of transcription factors binding sites in no-mediated histone H2B promoter repression]." dans: Molekuliarnaia biologiia, Vol. 43, Issue 2, pp. 368-73, (2009) (PubMed).

Dai, Yu, Goh, Chng, Tan, Fu, Zheng, Luo: "Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox status." dans: The Journal of biological chemistry, Vol. 283, Issue 40, pp. 26894-901, (2008) (PubMed).

Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." dans: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

Kawasaki, Schiltz, Chiu, Itakura, Taira, Nakatani, Yokoyama: "ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation." dans: Nature, Vol. 405, Issue 6783, pp. 195-200, (2000) (PubMed).

Détails sur HIST2H2BE

Antigène: HIST2H2BE (Histone H2B Type 2-E (HIST2H2BE))

Autre désignation: HIST2H2BE (HIST2H2BE Produits)

Synonymes: anticorps RGD1562346, anticorps AV127319, anticorps H2b-613, anticorps T25626, anticorps DKFZp469C0528, anticorps H2b, anticorps GL105, anticorps H2B, anticorps H2B.1, anticorps H2BFQ, anticorps H2BGL105, anticorps H2BQ, anticorps histone cluster 2 H2B family member E, anticorps histone cluster 2, H2be, anticorps histone cluster 1, H2bl, anticorps histone cluster 2 H2B family member e, anticorps histone H2B, anticorps Hist2h2be, anticorps HIST2H2BE, anticorps Hist1h2bl, anticorps H2B

Sujet: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Poids moléculaire: 13920

NCBI Accession: NP_003519

UniProt: Q16778