LGALS3BP anticorps (AA 383-412)

N° du produit ABIN1881492

Détail du produit anti-LGALS3BP anticorps

Antigène: LGALS3BP (Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP))

Épitope: AA 383-412

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGALS3BP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LGALS3BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-412 amino acids from the Central region of human LGALS3BP.

Clone: RB40516

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:2000. IHC-P-Leica: 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-LGALS3BP (ABIN1881492)

Srirajaskanthan, Caplin, Waugh, Watkins, Meyer, Hsuan, Beaumont: "Identification of Mac-2-binding protein as a putative marker of neuroendocrine tumors from the analysis of cell line secretomes." dans: Molecular & cellular proteomics : MCP, Vol. 9, Issue 4, pp. 656-66, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." dans: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Zambelli, Zuntini, Nardi, Manara, Serra, Landuzzi, Lollini, Ferrari, Alberghini, Llombart-Bosch, Piccolo, Iacobelli, Picci, Scotlandi: "Biological indicators of prognosis in Ewing's sarcoma: an emerging role for lectin galactoside-binding soluble 3 binding protein (LGALS3BP)." dans: International journal of cancer. Journal international du cancer, Vol. 126, Issue 1, pp. 41-52, (2009) (PubMed).

Lee, Zhang, Shin, Lee, Kim: "Mac-2 binding protein and galectin-3 expression in mucinous tumours of the ovary: an annealing control primer system and immunohistochemical study." dans: Pathology, Vol. 41, Issue 3, pp. 229-33, (2009) (PubMed).

Kim, Lee, Sung, Choi, Choi, Kim, Kim, Yu, Hwang, Kim: "Increased serum 90K and Galectin-3 expression are associated with advanced stage and a worse prognosis in diffuse large B-cell lymphomas." dans: Acta haematologica, Vol. 120, Issue 4, pp. 211-6, (2009) (PubMed).

Détails sur LGALS3BP

Antigène: LGALS3BP (Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP))

Autre désignation: LGALS3BP (LGALS3BP Produits)

Synonymes: anticorps 90K, anticorps BTBD17B, anticorps MAC-2-BP, anticorps TANGO10B, anticorps Ppicap, anticorps CyCAP, anticorps MAC-2BP, anticorps Tango10b, anticorps lgals3bp, anticorps zgc:136780, anticorps MAC2BP, anticorps Mac-2 BP, anticorps zgc:77059, anticorps galectin 3 binding protein, anticorps lectin, galactoside-binding, soluble, 3 binding protein, anticorps calcium activated nucleotidase 1, anticorps lectin, galactoside-binding, soluble, 3 binding protein a, anticorps lectin, galactoside-binding, soluble, 3 binding protein b, anticorps LGALS3BP, anticorps Lgals3bp, anticorps CANT1, anticorps lgals3bpa, anticorps lgals3bpb

Sujet: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.

NCBI Accession: NP_005558

UniProt: Q08380