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CDKN1B anticorps (N-Term)

CDKN1B Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB42097 unconjugated
N° du produit ABIN1881620
  • Antigène Voir toutes CDKN1B Anticorps
    CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
    Épitope
    • 29
    • 28
    • 22
    • 19
    • 17
    • 16
    • 11
    • 10
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivité
    • 277
    • 128
    • 108
    • 26
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 240
    • 52
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 231
    • 65
    Polyclonal
    Conjugué
    • 146
    • 24
    • 17
    • 16
    • 16
    • 14
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp CDKN1B est non-conjugé
    Application
    • 205
    • 134
    • 74
    • 62
    • 53
    • 41
    • 36
    • 26
    • 25
    • 16
    • 16
    • 13
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Ha
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This p27Kip1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human p27Kip1.
    Clone
    RB42097
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CDKN1B Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Kajihara, Fukushige, Shioda, Tanabe, Fukunaga, Inui: "CaMKII phosphorylates serine 10 of p27 and confers apoptosis resistance to HeLa cells." dans: Biochemical and biophysical research communications, Vol. 401, Issue 3, pp. 350-5, (2010) (PubMed).

    Kedde, van Kouwenhove, Zwart, Oude Vrielink, Elkon, Agami: "A Pumilio-induced RNA structure switch in p27-3' UTR controls miR-221 and miR-222 accessibility." dans: Nature cell biology, Vol. 12, Issue 10, pp. 1014-20, (2010) (PubMed).

    Canbay, Eraltan, Cercel, Isbir, Gazioglu, Aydogan, Cacina, Cengiz, Ferahman, Zengin, Unal: "CCND1 and CDKN1B polymorphisms and risk of breast cancer." dans: Anticancer research, Vol. 30, Issue 7, pp. 3093-8, (2010) (PubMed).

    Do Nascimento Borges, Burbano, Harada: "Absence of CIP1/KIP1 hypermethylation in gastric cancer patients from Northern Brazil." dans: In vivo (Athens, Greece), Vol. 24, Issue 4, pp. 579-82, (2010) (PubMed).

  • Antigène
    CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
    Autre désignation
    p27Kip1 (CDKN1B Produits)
    Synonymes
    anticorps CDKN4, anticorps KIP1, anticorps MEN1B, anticorps MEN4, anticorps P27KIP1, anticorps cdkn1b, anticorps sb:cb611, anticorps wu:fb63g10, anticorps wu:fb64g10, anticorps wu:fe18e03, anticorps CDKN1B, anticorps Kip1, anticorps p27, anticorps FAM14D, anticorps ISG12, anticorps ISG12A, anticorps P27, anticorps Cdki1b, anticorps AA408329, anticorps AI843786, anticorps p27Kip1, anticorps cdkn1bl, anticorps cyclin dependent kinase inhibitor 1B, anticorps cyclin-dependent kinase inhibitor 1Bb, anticorps interferon alpha inducible protein 27, anticorps cyclin-dependent kinase inhibitor 1B, anticorps cyclin-dependent kinase inhibitor 1Ba, anticorps CDKN1B, anticorps cdkn1bb, anticorps IFI27, anticorps Cdkn1b, anticorps cdkn1ba
    Sujet
    This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq].
    Poids moléculaire
    22073
    NCBI Accession
    NP_004055
    UniProt
    P46527
    Pathways
    Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy
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