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Progesterone Receptor anticorps (AA 523-550)

PGR Reactivité: Humain WB Hôte: Lapin Polyclonal RB41474 unconjugated
N° du produit ABIN1881649
  • Antigène Voir toutes Progesterone Receptor (PGR) Anticorps
    Progesterone Receptor (PGR)
    Épitope
    • 16
    • 16
    • 15
    • 14
    • 13
    • 12
    • 11
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 523-550
    Reactivité
    • 239
    • 42
    • 38
    • 16
    • 15
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 181
    • 60
    • 1
    • 1
    Lapin
    Clonalité
    • 175
    • 68
    Polyclonal
    Conjugué
    • 120
    • 21
    • 11
    • 11
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Progesterone Receptor est non-conjugé
    Application
    • 176
    • 90
    • 57
    • 32
    • 29
    • 26
    • 26
    • 25
    • 18
    • 18
    • 17
    • 12
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This PGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-550 amino acids from the Central region of human PGR.
    Clone
    RB41474
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PGR Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Van Belle, Van Calster, Brouckaert, Vanden Bempt, Pintens, Harvey, Murray, Naume, Wiedswang, Paridaens, Moerman, Amant, Leunen, Smeets, Drijkoningen, Wildiers, Christiaens, Vergote, Van Huffel, Neven: "Qualitative assessment of the progesterone receptor and HER2 improves the Nottingham Prognostic Index up to 5 years after breast cancer diagnosis." dans: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 28, Issue 27, pp. 4129-34, (2010) (PubMed).

    Geradts, Bean, Bentley, Barry: "The oncotype DX recurrence score is correlated with a composite index including routinely reported pathobiologic features." dans: Cancer investigation, Vol. 28, Issue 9, pp. 969-77, (2010) (PubMed).

    Tang, Wang, Hicks, Wang, Schiffhauer, McMahon, Yang, Shayne, Huston, Skinner, Griggs, Lyman: "A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer." dans: Cancer investigation, Vol. 28, Issue 9, pp. 978-82, (2010) (PubMed).

  • Antigène
    Progesterone Receptor (PGR)
    Autre désignation
    PGR (PGR Produits)
    Synonymes
    anticorps NR3C3, anticorps PR, anticorps 9930019P03Rik, anticorps BB114106, anticorps ENSMUSG00000074510, anticorps PR-A, anticorps PR-B, anticorps XPR-1, anticorps pgr, anticorps xpr-2, anticorps LOC443444, anticorps PGR, anticorps pg, anticorps pr, anticorps gb:dq017620, anticorps progesterone receptor, anticorps progesterone receptor L homeolog, anticorps PGR, anticorps Pgr, anticorps pgr.L, anticorps pgr
    Sujet
    This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.
    Poids moléculaire
    98981
    NCBI Accession
    NP_000917, NP_001189403, NP_001258091
    UniProt
    P06401
    Pathways
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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