PIGB anticorps (N-Term)

N° du produit ABIN1881653

Détail du produit anti-PIGB anticorps

Antigène: PIGB (Phosphatidylinositol Glycan Anchor Biosynthesis, Class B (PIGB))

Épitope: AA 28-56, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIGB est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PIGB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human PIGB.

Clone: RB32518

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PIGB (ABIN1881653)

Hwang, Hayashi, Kita, Takahashi, Kuge, Naganuma: "siRNA-mediated inhibition of phosphatidylinositol glycan Class B (PIGB) confers resistance to methylmercury in HEK293 cells." dans: The Journal of toxicological sciences, Vol. 32, Issue 5, pp. 581-3, (2008) (PubMed).

Anikster, Huizing, Anderson, Fitzpatrick, Klar, Gross-Kieselstein, Berkun, Shazberg, Gahl, Hurvitz: "Evidence that Griscelli syndrome with neurological involvement is caused by mutations in RAB27A, not MYO5A." dans: American journal of human genetics, Vol. 71, Issue 2, pp. 407-14, (2002) (PubMed).

Kinoshita, Inoue: "Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis." dans: Current opinion in chemical biology, Vol. 4, Issue 6, pp. 632-8, (2001) (PubMed).

Takahashi, Inoue, Ohishi, Maeda, Nakamura, Endo, Fujita, Takeda, Kinoshita: "PIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor." dans: The EMBO journal, Vol. 15, Issue 16, pp. 4254-61, (1996) (PubMed).

Détails sur PIGB

Antigène: PIGB (Phosphatidylinositol Glycan Anchor Biosynthesis, Class B (PIGB))

Autre désignation: PIGB (PIGB Produits)

Synonymes: anticorps GPI-MT-III, anticorps PIG-B, anticorps Pig-b, anticorps phosphatidylinositol glycan anchor biosynthesis, class B, anticorps phosphatidylinositol glycan anchor biosynthesis class B, anticorps phosphatidylinositol glycan anchor biosynthesis class B S homeolog, anticorps Pigb, anticorps PIGB, anticorps pigb.S

Sujet: This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases.

Poids moléculaire: 65056

NCBI Accession: NP_004846

UniProt: Q92521

Pathways: Inositol Metabolic Process