SCARB1 anticorps (Scavenger Receptor Class B, Member 1) (AA 72-101)

Details for Product anti-SCARB1 Antibody No. ABIN1881777, Fournisseur: Connectez-vous pour afficher
Antigène
  • cb1015
  • SCARB1
  • Scarb1
  • CD36L1
  • CLA-1
  • CLA1
  • HDLQTL6
  • SR-BI
  • SRB1
  • AI120173
  • CD36
  • Cd36l1
  • Cla-1
  • Cla1
  • D5Ertd460e
  • Hdlq1
  • Hlb398
  • SR-B1
  • SRBI
  • Srb1
  • mSR-BI
  • scavenger receptor class B, member 1
  • scavenger receptor class B member 1
  • scarb1
  • SCARB1
  • Scarb1
  • CpipJ_CPIJ014332
  • CpipJ_CPIJ019101
Épitope
AA 72-101, N-Term
15
14
12
5
5
2
2
2
1
1
1
1
Reactivité
Humain
83
43
40
2
2
2
2
1
Hôte
Lapin
75
17
14
Clonalité (Clone)
Polyclonal ()
Conjugué
Cet anticorp SCARB1 est non-conjugé
4
4
3
3
2
2
1
1
1
Application
Western Blotting (WB)
89
45
41
22
13
12
10
7
6
5
3
1
1
1
1
Options
Fournisseur
Connectez-vous pour afficher
N° du produit (Fournisseur)
Connectez-vous pour afficher
Immunogène This SCARB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of human SCARB1.
Clone RB41754
Homologie Pig (Porcine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Plasmids, Primers & others Plasmids, Primers & others SCARB1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation SCARB1 (SCARB1 Antibody Extrait)
Sujet Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester (By similarity).

Synonyms: SCARB1, CD36L1, CLA1, Scavenger receptor class B member 1, CD36 and LIMPII analogous 1, CD36 antigen-like 1, Collagen type I receptor, thrombospondin receptor-like 1, SR-BI, CD_antigen=CD36
NCBI Accession NP_005496
UniProt Q8WTV0
Pathways Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism
Indications d'application WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Images (Fournisseur)
Western Blotting (WB) image for anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 72-101), (N-Term) antibody (ABIN1881777) SCARB1 Antibody (N-term) (ABIN1881777) western blot analysis in A549 cell line lysate...
Produit citée dans: Kolmakova, Wang, Brogan, Chaffin, Rodriguez: "Deficiency of scavenger receptor class B type I negatively affects progesterone secretion in human granulosa cells." dans: Endocrinology, Vol. 151, Issue 11, pp. 5519-27, 2010 (PubMed).

Teslovich, Musunuru, Smith, Edmondson, Stylianou, Koseki, Pirruccello, Ripatti, Chasman, Willer, Johansen, Fouchier, Isaacs, Peloso, Barbalic, Ricketts, Bis, Aulchenko, Thorleifsson, Feitosa et al.: "Biological, clinical and population relevance of 95 loci for blood lipids. ..." dans: Nature, Vol. 466, Issue 7307, pp. 707-13, 2010 (PubMed).

Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." dans: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Ruaño, Thompson, Kane, Pullinger, Windemuth, Seip, Kocherla, Holford, Wu: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" dans: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

Avez-vous cherché autre chose?