SHC4 anticorps (C-Term)

N° du produit ABIN1881806

Détail du produit anti-SHC4 anticorps

Antigène: SHC4 (SHC (Src Homology 2 Domain Containing) Family, Member 4 (SHC4))

Épitope: AA 590-617, C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHC4 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Shc4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 590-617 amino acids from the C-terminal region of mouse Shc4.

Clone: RB40853

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-SHC4 (ABIN1881806)

Jones, Hardy, Friese, Jorgensen, Smith, Woody, Burden, Pawson: "Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase." dans: Molecular and cellular biology, Vol. 27, Issue 13, pp. 4759-73, (2007) (PubMed).

Fagiani, Giardina, Luzi, Cesaroni, Quarto, Capra, Germano, Bono, Capillo, Pelicci, Lanfrancone: "RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas." dans: Cancer research, Vol. 67, Issue 7, pp. 3064-73, (2007) (PubMed).

Détails sur SHC4

Antigène: SHC4 (SHC (Src Homology 2 Domain Containing) Family, Member 4 (SHC4))

Autre désignation: Shc4 (SHC4 Produits)

Synonymes: anticorps RGD1309182, anticorps RaLP, anticorps SHCD, anticorps 6230417E10Rik, anticorps 9930029B02Rik, anticorps Gm685, anticorps SHC adaptor protein 4, anticorps SHC (Src homology 2 domain containing) family, member 4, anticorps Shc4, anticorps SHC4

Sujet: Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.

Poids moléculaire: 68519

NCBI Accession: NP_950187

UniProt: Q6S5L9