SLC5A8 anticorps (C-Term)

N° du produit ABIN1881812

Détail du produit anti-SLC5A8 anticorps

Antigène: SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))

Épitope: AA 548-574, C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC5A8 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Slc5a8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-574 amino acids from the C-terminal region of mouse Slc5a8.

Clone: RB40849

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-SLC5A8 (ABIN1881812)

Cresci, Thangaraju, Mellinger, Liu, Ganapathy: "Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8." dans: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, Vol. 14, Issue 3, pp. 449-61, (2010) (PubMed).

Détails sur SLC5A8

Antigène: SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))

Autre désignation: Slc5a8 (SLC5A8 Produits)

Synonymes: anticorps Ait, anticorps SMCT, anticorps SMCT1, anticorps AIT, anticorps RGD1564146, anticorps solute carrier family 5 (iodide transporter), member 8, anticorps solute carrier family 5 member 8, anticorps Slc5a8, anticorps SLC5A8

Sujet: Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.

Poids moléculaire: 66766

NCBI Accession: NP_663398

UniProt: Q8BYF6