SMAD6 anticorps (C-Term)

N° du produit ABIN1881817

Détail du produit anti-SMAD6 anticorps

Antigène: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Épitope: AA 357-386, C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD6 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SMAD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 357-386 amino acids from the C-terminal region of human SMAD6.

Clone: RB41931

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-SMAD6 (ABIN1881817)

Ryan, Ryan, Fabre, Lawless, Crowe: "Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis." dans: Hepatology (Baltimore, Md.), Vol. 52, Issue 4, pp. 1266-73, (2010) (PubMed).

Yu, Mrowietz, Seifert: "Downregulation of SMAD2, 4 and 6 mRNA and TGFbeta receptor I mRNA in lesional and non-lesional psoriatic skin." dans: Acta dermato-venereologica, Vol. 89, Issue 4, pp. 351-6, (2009) (PubMed).

Détails sur SMAD6

Antigène: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Autre désignation: SMAD6 (SMAD6 Produits)

Synonymes: anticorps madh6, anticorps madh7, anticorps Xsmad6, anticorps hst17432, anticorps AOVD2, anticorps HsT17432, anticorps MADH6, anticorps MADH7, anticorps Madh6, anticorps b2b390Clo, anticorps Smad6-like, anticorps smad6, anticorps wu:fb22g05, anticorps SMAD family member 6, anticorps SMAD family member 6a, anticorps smad6, anticorps SMAD6, anticorps Smad6, anticorps smad6a

Sujet: The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 53497

NCBI Accession: NP_001136333, NP_005576

UniProt: O43541

Pathways: Chromatin Binding