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SUPV3L1 anticorps (N-Term)

SUPV3L1 Reactivité: Humain, Souris, Rat WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB24555 unconjugated
N° du produit ABIN1881857
  • Antigène Voir toutes SUPV3L1 Anticorps
    SUPV3L1 (Suppressor of Var1, 3-Like 1 (SUPV3L1))
    Épitope
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 93-121, N-Term
    Reactivité
    • 16
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 13
    • 3
    Lapin
    Clonalité
    • 15
    • 1
    Polyclonal
    Conjugué
    • 13
    • 1
    • 1
    • 1
    Cet anticorp SUPV3L1 est non-conjugé
    Application
    • 12
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This SUPV3L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-121 amino acids from the N-terminal region of human SUPV3L1.
    Clone
    RB24555
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Szczesny, Borowski, Brzezniak, Dmochowska, Gewartowski, Bartnik, Stepien: "Human mitochondrial RNA turnover caught in flagranti: involvement of hSuv3p helicase in RNA surveillance." dans: Nucleic acids research, Vol. 38, Issue 1, pp. 279-98, (2010) (PubMed).

    Wang, Shu, Lieser, Chen, Lee: "Human mitochondrial SUV3 and polynucleotide phosphorylase form a 330-kDa heteropentamer to cooperatively degrade double-stranded RNA with a 3'-to-5' directionality." dans: The Journal of biological chemistry, Vol. 284, Issue 31, pp. 20812-21, (2009) (PubMed).

    Khidr, Wu, Davila, Procaccio, Wallace, Lee: "Role of SUV3 helicase in maintaining mitochondrial homeostasis in human cells." dans: The Journal of biological chemistry, Vol. 283, Issue 40, pp. 27064-73, (2008) (PubMed).

    Bogenhagen, Rousseau, Burke: "The layered structure of human mitochondrial DNA nucleoids." dans: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3665-75, (2008) (PubMed).

    Pereira, Mason, Szczesny, Maddukuri, Dziwura, Jedrzejczak, Paul, Wojcik, Dybczynska, Tudek, Bartnik, Klysik, Bohr, Stepien: "Interaction of human SUV3 RNA/DNA helicase with BLM helicase; loss of the SUV3 gene results in mouse embryonic lethality." dans: Mechanisms of ageing and development, Vol. 128, Issue 11-12, pp. 609-17, (2007) (PubMed).

  • Antigène
    SUPV3L1 (Suppressor of Var1, 3-Like 1 (SUPV3L1))
    Autre désignation
    SUPV3L1 (SUPV3L1 Produits)
    Synonymes
    anticorps SUV3, anticorps 6330443E10Rik, anticorps wu:fc19b02, anticorps wu:fe37e06, anticorps Suv3 like RNA helicase, anticorps suppressor of var1, 3-like 1 (S. cerevisiae), anticorps SUV3-like helicase, anticorps SUPV3L1, anticorps Supv3l1, anticorps supv3l1
    Sujet
    SUV3L1 is an ATPase and DNA/RNA helicase able to unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes in the 5'-3' direction. It may protect cells from apoptosis.
    Poids moléculaire
    87991
    NCBI Accession
    NP_003162
    UniProt
    Q8IYB8
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