UGT2B4 anticorps (N-Term)

N° du produit ABIN1881977

Détail du produit anti-UGT2B4 anticorps

Antigène: UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))

Épitope: AA 68-96, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UGT2B4 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This UGT2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of human UGT2B4.

Clone: RB41766

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:8000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-UGT2B4 (ABIN1881977)

Lévesque, Ménard, Laverdière, Bellemare, Barbier, Girard, Guillemette: "Extensive splicing of transcripts encoding the bile acid-conjugating enzyme UGT2B4 modulates glucuronidation." dans: Pharmacogenetics and genomics, Vol. 20, Issue 3, pp. 195-210, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Yong, Schwartz, Atkinson, Makar, Thomas, Newton, Aiello Bowles, Holt, Leisenring, Lampe: "Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States." dans: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 2, pp. 537-46, (2010) (PubMed).

Détails sur UGT2B4

Antigène: UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))

Autre désignation: UGT2B4 (UGT2B4 Produits)

Synonymes: anticorps HLUG25, anticorps UDPGTH1, anticorps UGT2B11, anticorps UDPGT2B4, anticorps UGT2B17, anticorps UGT2B28, anticorps UDP glucuronosyltransferase family 2 member B4, anticorps UDP-glucuronosyltransferase 2B4, anticorps UGT2B4, anticorps LOC615303, anticorps LOC100066359

Sujet: UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.

Poids moléculaire: 60513

NCBI Accession: NP_066962

UniProt: P06133

Pathways: Steroid Hormone Biosynthesis