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YBX1 anticorps (AA 149-178)

YBX1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal RB41913 unconjugated
N° du produit ABIN1882002
  • Antigène Voir toutes YBX1 Anticorps
    YBX1 (Y Box Binding Protein 1 (YBX1))
    Épitope
    • 26
    • 9
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 149-178
    Reactivité
    • 115
    • 76
    • 63
    • 21
    • 19
    • 18
    • 17
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 106
    • 11
    Lapin
    Clonalité
    • 96
    • 21
    Polyclonal
    Conjugué
    • 58
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp YBX1 est non-conjugé
    Application
    • 81
    • 26
    • 16
    • 16
    • 15
    • 15
    • 14
    • 10
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Homologie
    B, M, Rb, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This YBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the Central region of human YBX1.
    Clone
    RB41913
    Isotype
    Ig Fraction
    Top Product
    Discover our top product YBX1 Anticorps primaire
  • Indications d'application
    IF: 1:10~50. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Osada, Uno, Mineta, Kameoka, Takahashi, Terao: "Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta." dans: Molecular ecology, Vol. 19, Issue 14, pp. 2884-95, (2010) (PubMed).

    Yu, Yip, Tan, Thike, Matsumoto, Tsujimoto, Bay: "Y-box binding protein 1 is up-regulated in proliferative breast cancer and its inhibition deregulates the cell cycle." dans: International journal of oncology, Vol. 37, Issue 2, pp. 483-92, (2010) (PubMed).

    Lovett, Cheng, Cape, Pollock, Mertens: "YB-1 alters MT1-MMP trafficking and stimulates MCF-7 breast tumor invasion and metastasis." dans: Biochemical and biophysical research communications, Vol. 398, Issue 3, pp. 482-8, (2010) (PubMed).

    Takahashi, Shimajiri, Izumi, Hirano, Kashiwagi, Yasuniwa, Wu, Han, Akiyama, Nishizawa, Sasaguri, Kohno: "Y-box binding protein-1 is a novel molecular target for tumor vessels." dans: Cancer science, Vol. 101, Issue 6, pp. 1367-73, (2010) (PubMed).

    To, Fotovati, Reipas, Law, Hu, Wang, Astanehe, Davies, Lee, Stratford, Raouf, Johnson, Berquin, Royer, Eaves, Dunn: "Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance." dans: Cancer research, Vol. 70, Issue 7, pp. 2840-51, (2010) (PubMed).

  • Antigène
    YBX1 (Y Box Binding Protein 1 (YBX1))
    Autre désignation
    YBX1 (YBX1 Produits)
    Synonymes
    anticorps BP-8, anticorps CSDA2, anticorps CSDB, anticorps DBPB, anticorps MDR-NF1, anticorps NSEP-1, anticorps NSEP1, anticorps YB-1, anticorps YB1, anticorps Byb1, anticorps Cbfa, anticorps Dbpb, anticorps Ef1a, anticorps Msy1, anticorps Nsep1, anticorps Yb1, anticorps bp-8, anticorps csda2, anticorps csdb, anticorps dbpb, anticorps frgy1, anticorps mdr-nf1, anticorps nsep-1, anticorps nsep1, anticorps yb1, anticorps 1700102N10Rik, anticorps C79409, anticorps EF1A, anticorps MSY1, anticorps dbpB, anticorps mYB-1a, anticorps nuclease sensitive element binding protein 1, anticorps Y-box binding protein 1, anticorps Y box binding protein 1, anticorps Y-box binding protein 1 S homeolog, anticorps nuclease-sensitive element-binding protein 1, anticorps Y box protein 1, anticorps nsep1, anticorps YBX1, anticorps Ybx1, anticorps ybx1.S, anticorps LOC479011
    Sujet
    Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability.
    Poids moléculaire
    35924
    NCBI Accession
    NP_004550
    UniProt
    P67809
    Pathways
    Regulation of Muscle Cell Differentiation
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