Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This ZRSR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-482 amino acids from the C-terminal region of human ZRSR2.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
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Scanlan, Gordan, Williamson, Stockert, Bander, Jongeneel, Gure, Jäger, Jäger, Knuth, Chen, Old: "Antigens recognized by autologous antibody in patients with renal-cell carcinoma." dans: International journal of cancer. Journal international du cancer, Vol. 83, Issue 4, pp. 456-64, (1999) (PubMed).
Tronchère, Wang, Fu: "A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA." dans: Nature, Vol. 388, Issue 6640, pp. 397-400, (1997) (PubMed).
Kitagawa, Wang, Hatada, Yamaoka, Nojima, Inazawa, Abe, Mitsuya, Oshimura, Murata: "Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1." dans: Genomics, Vol. 30, Issue 2, pp. 257-63, (1996) (PubMed).
Pre-mRNA-binding protein required for splicing of both U2-and U12-type introns. Selectively interacts with the 3'-splice site of U2-and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing.