ARL6 anticorps (N-Term)

N° du produit ABIN1882064

Détail du produit anti-ARL6 anticorps

Antigène: ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Épitope: AA 1-30, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARL6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ARL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ARL6.

Clone: RB4921

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ARL6 (ABIN1882064)

Wiens, Tong, Esmail, Oh, Gerdes, Wang, Tempel, Rattner, Katsanis, Park, Leroux: "Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling." dans: The Journal of biological chemistry, Vol. 285, Issue 21, pp. 16218-30, (2010) (PubMed).

Pasqualato, Renault, Cherfils: "Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication." dans: EMBO reports, Vol. 3, Issue 11, pp. 1035-41, (2002) (PubMed).

Ingley, Williams, Walker, Tsai, Colley, Sayer, Tilbrook, Sarna, Beaumont, Klinken: "A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit." dans: FEBS letters, Vol. 459, Issue 1, pp. 69-74, (1999) (PubMed).

Jacobs, Schilf, Fliegert, Koling, Weber, Schürmann, Joost: "ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARF family characterization by rapid nucleotide exchange and a nuclear localization signal." dans: FEBS letters, Vol. 456, Issue 3, pp. 384-8, (1999) (PubMed).

Détails sur ARL6

Antigène: ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Autre désignation: ARL6 (ARL6 Produits)

Synonymes: anticorps BBS3, anticorps RP55, anticorps 1110018H24Rik, anticorps 2210411E14Rik, anticorps zgc:101762, anticorps arl6, anticorps ADP ribosylation factor like GTPase 6, anticorps ADP-ribosylation factor-like 6, anticorps ADP-ribosylation factor like GTPase 6, anticorps ADP-ribosylation factor-like protein 6, anticorps ADP ribosylation factor like GTPase 6 L homeolog, anticorps ARL6, anticorps Arl6, anticorps arl6, anticorps arl-6, anticorps arl6.L

Sujet: ARL6 belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described.

Poids moléculaire: 21097

NCBI Accession: NP_001265222, NP_115522, NP_816931

UniProt: Q9H0F7