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CYP2C9 anticorps (N-Term)

CYP2C9 Reactivité: Humain WB Hôte: Souris Monoclonal 682CT5-6-2 unconjugated
N° du produit ABIN1882233
  • Antigène Voir toutes CYP2C9 Anticorps
    CYP2C9 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))
    Épitope
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 82-110, N-Term
    Reactivité
    • 25
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 25
    Souris
    Clonalité
    • 25
    Monoclonal
    Conjugué
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CYP2C9 est non-conjugé
    Application
    • 21
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
    Immunogène
    This CYP2C9 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the N-terminal region of human CYP2C9.
    Clone
    682CT5-6-2
    Isotype
    IgM
    Top Product
    Discover our top product CYP2C9 Anticorps primaire
  • Indications d'application
    WB: 1:100~1600
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Yang, Cui, Hasi, Jia, Gong, Su: "Genetic polymorphisms of cytochrome P450 enzymes 2C9 and 2C19 in a healthy Mongolian population in China." dans: Genetics and molecular research : GMR, Vol. 9, Issue 3, pp. 1844-51, (2010) (PubMed).

    Ikejiri, Wada, Sakamoto, Ito, Nishioka, Nakatani, Tsuji, Yamada, Nakamura, Ito, Nobori: "The association of protein S Tokushima-K196E with a risk of deep vein thrombosis." dans: International journal of hematology, Vol. 92, Issue 2, pp. 302-5, (2010) (PubMed).

    Schelleman, Brensinger, Chen, Finkelman, Rieder, Kimmel: "New genetic variant that might improve warfarin dose prediction in African Americans." dans: British journal of clinical pharmacology, Vol. 70, Issue 3, pp. 393-9, (2010) (PubMed).

  • Antigène
    CYP2C9 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))
    Autre désignation
    CYP2C9 (CYP2C9 Produits)
    Synonymes
    anticorps CPC9, anticorps CYP2C, anticorps CYP2C10, anticorps CYPIIC9, anticorps P450IIC9, anticorps cytochrome P450 family 2 subfamily C member 9, anticorps CYP2C9
    Sujet
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
    Poids moléculaire
    55628
    NCBI Accession
    NP_000762
    UniProt
    P11712
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