LRFN4
Reactivité: Humain, Souris, Rat
WB, ELISA, IHC (p), IF
Hôte: Lapin
Polyclonal
unconjugated
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Conseil sur la manipulation
Avoid freezing and thawing repeatly.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Antigène
LRFN4
(Leucine Rich Repeat and Fibronectin Type III Domain Containing 4 (LRFN4))
anticorps FIGLER6, anticorps SALM3, anticorps SALM3., anticorps BC023156, anticorps Salm3, anticorps leucine rich repeat and fibronectin type III domain containing 4, anticorps LRFN4, anticorps Lrfn4
Sujet
LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues.LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins.Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells.LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery.It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.At least two isoforms of LRFN4 are known to exist. Synonyms: Leucine-rich repeat and fibronectin typeIII domain-containing protein 4, synaptic adhesion-like molecule 3, SALM3, FIGLER6