MYZAP anticorps (C-Term)

N° du produit ABIN1887247

Détail du produit anti-MYZAP anticorps

Antigène: MYZAP (Myocardial Zonula Adherens Protein (MYZAP))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYZAP est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Multiple isoforms of MYOZAP are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid peptide near the carboxy terminus of human MYOZAP.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur MYZAP

Antigène: MYZAP (Myocardial Zonula Adherens Protein (MYZAP))

Autre désignation: MYOZAP (MYZAP Produits)

Synonymes: anticorps AA407270, anticorps AV006038, anticorps Gcom1, anticorps Gm640, anticorps Grinl1a7, anticorps Myozap, anticorps Myzap, anticorps GLURR2, anticorps GRINL1B, anticorps GCOM1, anticorps Gup, anticorps Gup1, anticorps Gup2, anticorps MYOZAP, anticorps myocardial zonula adherens protein, anticorps GRINL1B complex locus 2 (pseudogene), anticorps Myzap, anticorps GCOM2, anticorps MYZAP

Sujet: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein.It is strongly expressed in the heart and lung and is a novel component of intercalated disc.MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling.Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction.The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A).Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
Synonyms: Myocardium-enriched zonula occludens-1

NCBI Accession: NP_001018110