SIGLEC11 anticorps (C-Term)

N° du produit ABIN1887430

Détail du produit anti-SIGLEC11 anticorps

Antigène: SIGLEC11 (Sialic Acid Binding Ig-Like Lectin 11 (SIGLEC11))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIGLEC11 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Purification: Affinity chromatography purified via peptide column

Immunogène: Siglec11 antibody was raised against an 18 amino acid peptide from near the carboxy terminus of human Siglec11.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur SIGLEC11

Antigène: SIGLEC11 (Sialic Acid Binding Ig-Like Lectin 11 (SIGLEC11))

Autre désignation: Siglec11 (SIGLEC11 Produits)

Synonymes: anticorps sialic acid binding Ig like lectin 11, anticorps SIGLEC11

Sujet: Siglecs are sialic acid-binding lectins of the immunoglobulin superfamily that are mainly expressed in cells of the hematopoietic system.Siglec11 is unlike other siglecs in that it binds specifically to alpha2-8-linked sialic acids and is not found in peripheral blood leukocytes but instead on macrophages of various tissues.Siglec11 is highly homologous to Siglec10 over their extracellular domain but not over their cytoplasmic domain, suggesting that Siglec11 arose through gene duplication followed by a recombination event involving another ancestral siglec gene.Following treatment of Siglec11-transfected cells with pervanadate, Siglec11 becomes tyrosine-phosphorylated and strongly associates with SHP-1 and SHP-2.At least five isoforms of Siglec11 are known to exist.Siglec11 antibody will not cross-react with Siglec10.
Synonyms: Siglec11, Sialic acid binding Ig-like lectin 11

NCBI Accession: NP_443116