ARHGEF17 anticorps (Center)

N° du produit ABIN1887696

Détail du produit anti-ARHGEF17 anticorps

Antigène: ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF17 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid peptide near the center of human TEM4.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur ARHGEF17

Antigène: ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))

Autre désignation: TEM4 (ARHGEF17 Produits)

Synonymes: anticorps P164RHOGEF, anticorps TEM4, anticorps p164-RhoGEF, anticorps 8030463K16, anticorps AI428794, anticorps AW558066, anticorps BC035332, anticorps mKIAA0337, anticorps Rho guanine nucleotide exchange factor 17, anticorps Rho guanine nucleotide exchange factor (GEF) 17, anticorps ARHGEF17, anticorps Arhgef17

Sujet: Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions.TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain.TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart.It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation.Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues.TEM4 could also prove to be useful targets therapeutically.
Synonyms: Tumor endothelial marker 4, ARHGEF17, Rho guanine nucleotide exchange factor 17, p164RHOGEF

UniProt: Q96PE2