FKBP15 anticorps (N-Term)

N° du produit ABIN1887901

Détail du produit anti-FKBP15 anticorps

Antigène: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP15 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide from near the amino terminus of human FKBP15.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur FKBP15

Antigène: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Autre désignation: FKBP15 (FKBP15 Produits)

Synonymes: anticorps KIAA0674, anticorps DKFZp469F024, anticorps BB131447, anticorps C430014M02Rik, anticorps FKBO133, anticorps FKBP-133, anticorps FKBP-15, anticorps FKBP133, anticorps mKIAA0674, anticorps RGD1304816, anticorps PPP1R76, anticorps FK506 binding protein 15, anticorps si:ch211-208h16.4, anticorps FKBP15, anticorps si:ch211-208h16.4, anticorps Fkbp15

Sujet: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin.FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif.FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior.FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes.At least three isoforms of FKBP15 are known to exist.
Synonyms: FKBP15, FK506-binding protein homolog, FKBP133, WASP and FKBP-like, WAFL

NCBI Accession: NP_056073

Pathways: SARS-CoV-2 Protein Interactome