FCGR3B anticorps (N-Term)

N° du produit ABIN1944735

Détail du produit anti-FCGR3B anticorps

Antigène: FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))

Épitope: AA 12-47, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FCGR3B est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FCGR3B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-47 amino acids from the N-terminal region of human FCGR3B.

Clone: RB47719

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-FCGR3B (ABIN1944735)

Ravetch, Perussia: "Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions." dans: The Journal of experimental medicine, Vol. 170, Issue 2, pp. 481-97, (1989) (PubMed).

Peltz, Grundy, Lebo, Yssel, Barsh, Moore: "Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 3, pp. 1013-7, (1989) (PubMed).

Scallon, Scigliano, Freedman, Miedel, Pan, Unkeless, Kochan: "A human immunoglobulin G receptor exists in both polypeptide-anchored and phosphatidylinositol-glycan-anchored forms." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 13, pp. 5079-83, (1989) (PubMed).

Simmons, Seed: "The Fc gamma receptor of natural killer cells is a phospholipid-linked membrane protein." dans: Nature, Vol. 333, Issue 6173, pp. 568-70, (1988) (PubMed).

Détails sur FCGR3B

Antigène: FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))

Autre désignation: FCGR3B (FCGR3B Produits)

Synonymes: anticorps CD16, anticorps CD16b, anticorps FCG3, anticorps FCGR3, anticorps FCR-10, anticorps FCRIII, anticorps FCRIIIb, anticorps FcRIII, anticorps Fc fragment of IgG receptor IIIb, anticorps Fc receptor, IgG, low affinity III, anticorps Fc fragment of IgG receptor IIIa, anticorps Fc-gamma RIII, anticorps FCGR3B, anticorps Fcgr3, anticorps FCGR3A, anticorps FCGR3

Sujet: Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

Poids moléculaire: 26216

ID gène: 2215

UniProt: O75015