MAFK anticorps

N° du produit ABIN1944786

Détail du produit anti-MAFK anticorps

Antigène: MAFK (Transcription Factor MafK (MAFK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAFK est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This MAFK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human MAFK.

Clone: 1328CT786-105-125

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:1000. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-MAFK (ABIN1944786)

Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: "The DNA sequence of human chromosome 7. ..." dans: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).

Toki, Itoh, Kitazawa, Arai, Hatakeyama, Akasaka, Igarashi, Nomura, Yokoyama, Yamamoto, Ito: "Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif." dans: Oncogene, Vol. 14, Issue 16, pp. 1901-10, (1997) (PubMed).

Détails sur MAFK

Antigène: MAFK (Transcription Factor MafK (MAFK))

Autre désignation: MAFK (MAFK Produits)

Synonymes: anticorps NFE2U, anticorps P18, anticorps AW061068, anticorps NF-E2, anticorps Nfe2u, anticorps MAF bZIP transcription factor K, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian), anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K, anticorps Mafk, anticorps MAFK, anticorps mafk

Sujet: Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.

Poids moléculaire: 17523

ID gène: 7975

UniProt: O60675