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MAGED1 anticorps (AA 20-224)

MAGED1 Reactivité: Humain WB Hôte: Souris Monoclonal 1305CT862-157-127 unconjugated
N° du produit ABIN1944790
  • Antigène Voir toutes MAGED1 Anticorps
    MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
    Épitope
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-224
    Reactivité
    • 39
    • 15
    • 14
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 32
    • 6
    • 1
    Souris
    Clonalité
    • 35
    • 4
    Monoclonal
    Conjugué
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MAGED1 est non-conjugé
    Application
    • 25
    • 12
    • 12
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogène
    This MAGED1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 20-224 amino acids from the Central region of human MAGED1.
    Clone
    1305CT862-157-127
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product MAGED1 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Wen, Xue, Qin, Yu, Zhang, Zhao, Gao, Gu, Li: "hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation." dans: FEBS letters, Vol. 564, Issue 1-2, pp. 171-6, (2004) (PubMed).

    Salehi, Roux, Kubu, Zeindler, Bhakar, Tannis, Verdi, Barker: "NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis." dans: Neuron, Vol. 27, Issue 2, pp. 279-88, (2000) (PubMed).

    Põld, Zhou, Chen, Hall, Vescio, Berenson: "Identification of a new, unorthodox member of the MAGE gene family." dans: Genomics, Vol. 59, Issue 2, pp. 161-7, (1999) (PubMed).

  • Antigène
    MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
    Autre désignation
    MAGED1 (MAGED1 Produits)
    Synonymes
    anticorps MAGED1, anticorps DLXIN-1, anticorps NRAGE, anticorps 2810433C11Rik, anticorps 5430405L04Rik, anticorps DXBwg1492e, anticorps Dlixin, anticorps Dlxin-1, anticorps Dlxin1, anticorps MAGE-D1, anticorps mFLJ00163, anticorps Nrage, anticorps MAGE family member D1, anticorps melanoma antigen family D, 1, anticorps melanoma antigen, family D, 1, anticorps MAGED1, anticorps Maged1
    Sujet
    Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds NGFR/p75NTR and antagonizes its association with NTRK1/TrkA, inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate TP53/p53 transcriptional activity and inhibit cell proliferation. Enhances TP53 phosphorylation and accumulation. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
    Poids moléculaire
    86161
    ID gène
    9500
    UniProt
    Q9Y5V3
    Pathways
    Neurotrophin Signaling Pathway
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