TFAP2A anticorps (AA 134-166)

N° du produit ABIN1945094

Détail du produit anti-TFAP2A anticorps

Antigène: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Épitope: AA 134-166

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFAP2A est non-conjugé

Application: Western Blotting (WB)

Homologie: B, Rat, Sh

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This mouse Tfap2a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 134-166 amino acids from the Central region of mouse Tfap2a.

Clone: RB43450

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-TFAP2A (ABIN1945094)

Yahata, Takedatsu, Dunwoodie, Bragança, Swingler, Withington, Hur, Coser, Isselbacher, Bhattacharya, Shioda: "Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells." dans: Genomics, Vol. 80, Issue 6, pp. 601-13, (2002) (PubMed).

Meier, Koedood, Philipp, Fontana, Mitchell: "Alternative mRNAs encode multiple isoforms of transcription factor AP-2 during murine embryogenesis." dans: Developmental biology, Vol. 169, Issue 1, pp. 1-14, (1995) (PubMed).

Moser, Pscherer, Bauer, Imhof, Seegers, Kerscher, Buettner: "The complete murine cDNA sequence of the transcription factor AP-2." dans: Nucleic acids research, Vol. 21, Issue 20, pp. 4844, (1993) (PubMed).

Mitchell, Timmons, Hébert, Rigby, Tjian: "Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis." dans: Genes & development, Vol. 5, Issue 1, pp. 105-19, (1991) (PubMed).

Détails sur TFAP2A

Antigène: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Autre désignation: Tfap2a (TFAP2A Produits)

Synonymes: anticorps TFAP2A, anticorps Ap-2, anticorps AP-2, anticorps AP-2alpha, anticorps AP2TF, anticorps BOFS, anticorps TFAP2, anticorps ap2, anticorps xap2, anticorps XAP-2, anticorps ap2tf, anticorps tfap2, anticorps ap-2alpha, anticorps tfap2alpha, anticorps cb93, anticorps fb83f04, anticorps fc31a07, anticorps wu:fb83f04, anticorps wu:fc31a07, anticorps tfap2a-a, anticorps tcfap2a, anticorps ap2a, anticorps AP2alpha, anticorps Ap2, anticorps Ap2tf, anticorps Tcfap2a, anticorps AP2, anticorps transcription factor AP-2 alpha, anticorps transcription factor AP-2, anticorps tto transcription factor AP-2 alpha, anticorps to transcription factor AP-2 alpha L homeolog, anticorps to transcription factor AP-2 alpha S homeolog, anticorps Transcription factor AP-2 alpha, anticorps transcription factor AP-2, alpha, anticorps TFAP2A, anticorps LOC100302602, anticorps tfap2a, anticorps tfap2a.L, anticorps tfap2a.S, anticorps ap2a, anticorps Tfap2a

Sujet: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.

Poids moléculaire: 47971

ID gène: 21418

UniProt: P34056

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism