HSP90AA1 anticorps (AA 229-263)

N° du produit ABIN1945096

Détail du produit anti-HSP90AA1 anticorps

Antigène: HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))

Épitope: AA 229-263

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSP90AA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This hsp90a.1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 229-263 amino acids from the Central region of human (DANRE) hsp90a.1.

Clone: RB47443

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:2000. WB: 1:1000. WB: 1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-HSP90AA1 (ABIN1945096)

Howe, Clark, Torroja, Torrance, Berthelot, Muffato, Collins, Humphray, McLaren, Matthews, McLaren, Sealy, Caccamo, Churcher, Scott, Barrett, Koch, Rauch, White, Chow, Kilian, Quintais, Guerra-Assunção, Zhou, Gu, Yen, Vogel, Eyre, Redmond, Banerjee, Chi, F: "The zebrafish reference genome sequence and its relationship to the human genome." dans: Nature, Vol. 496, Issue 7446, pp. 498-503, (2013) (PubMed).

Etard, Roostalu, Strähle: "Shuttling of the chaperones Unc45b and Hsp90a between the A band and the Z line of the myofibril." dans: The Journal of cell biology, Vol. 180, Issue 6, pp. 1163-75, (2008) (PubMed).

Etard, Behra, Fischer, Hutcheson, Geisler, Strähle: "The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesis." dans: Developmental biology, Vol. 308, Issue 1, pp. 133-43, (2007) (PubMed).

Lele, Hartson, Martin, Whitesell, Matts, Krone: "Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90." dans: Developmental biology, Vol. 210, Issue 1, pp. 56-70, (1999) (PubMed).

Krone, Sass: "HSP 90 alpha and HSP 90 beta genes are present in the zebrafish and are differentially regulated in developing embryos." dans: Biochemical and biophysical research communications, Vol. 204, Issue 2, pp. 746-52, (1994) (PubMed).

Détails sur HSP90AA1

Antigène: HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))

Autre désignation: hsp90a.1 (HSP90AA1 Produits)

Synonymes: anticorps EL52, anticorps HSP86, anticorps HSP89A, anticorps HSP90A, anticorps HSP90N, anticorps HSPC1, anticorps HSPCA, anticorps HSPCAL1, anticorps HSPCAL4, anticorps HSPN, anticorps Hsp89, anticorps Hsp90, anticorps LAP2, anticorps Hsp86, anticorps Hspca, anticorps htpG, anticorps 86kDa, anticorps 89kDa, anticorps AL024080, anticorps AL024147, anticorps Hsp86-1, anticorps hsp4, anticorps HSP90, anticorps HSP90AA1, anticorps fb17b01, anticorps hsp90, anticorps hsp90a, anticorps hsp90a.1, anticorps hsp90alpha, anticorps wu:fb17b01, anticorps zgc:86652, anticorps Hsp90alpha, anticorps heat shock protein 90 alpha family class A member 1, anticorps heat shock protein 90, alpha (cytosolic), class A member 1, anticorps Heat Shock Protein 90, cytosolic, anticorps heat shock protein 90A, anticorps molecular chaperone, anticorps heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1, anticorps heat shock protein HSP 90-alpha, anticorps heat shock protein 90kDa alpha (cytosolic), class A member 1, anticorps HSP90AA1, anticorps Hsp90aa1, anticorps HSP90A, anticorps hsp90A, anticorps hsp90aa1.1, anticorps LOC108698781

Sujet: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Plays a key role in slow and fast muscle development in the embryo. Plays a role in myosin expression and assembly.

Poids moléculaire: 83319

ID gène: 30591

UniProt: Q90474

Pathways: M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals