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Ephrin B2 anticorps (AA 328-332)

EFNB2 Reactivité: Humain, Souris, Rat WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN197419
  • Antigène Voir toutes Ephrin B2 (EFNB2) Anticorps
    Ephrin B2 (EFNB2)
    Épitope
    • 10
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 328-332
    Reactivité
    • 58
    • 35
    • 29
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 53
    • 4
    • 1
    Lapin
    Clonalité
    • 45
    • 12
    Polyclonal
    Conjugué
    • 35
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Cet anticorp Ephrin B2 est non-conjugé
    Application
    • 35
    • 20
    • 14
    • 8
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Specificité
    This antibody AP02708PU detects endogenous levels of total Ephrin-B2 protein.
    Purification
    Immunoaffinity Chromatography using epitope-specific immunogen.
    Immunogène
    Peptide Sequence around amino acids 328~332 (N-I-Y-Y-K) derived from Human Ephrin-B2.
    Top Product
    Discover our top product EFNB2 Anticorps primaire
  • Indications d'application
    Western blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody (in aliquots) at -20 °C.
  • Antigène
    Ephrin B2 (EFNB2)
    Autre désignation
    Ephrin-B2 (EFNB2 Produits)
    Synonymes
    anticorps EFNB2, anticorps efnb2, anticorps ephrin-B2, anticorps htkl, anticorps eplg5, anticorps htk-l, anticorps lerk5, anticorps ephrinB2, anticorps efnb2a, anticorps MGC68890, anticorps efnb2b, anticorps ELF-2, anticorps Epl5, anticorps Eplg5, anticorps Htk-L, anticorps LERK-5, anticorps Lerk5, anticorps NLERK-1, anticorps EPLG5, anticorps HTKL, anticorps LERK5, anticorps ephrin B2, anticorps ephrin-B2 precursor, anticorps ephrin B2 L homeolog, anticorps ephrin B2 S homeolog, anticorps EFNB2, anticorps efnb2, anticorps efnb2.L, anticorps efnb2.S, anticorps Efnb2
    Sujet
    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP)and also interacts with PRKCABP and GRIP1. This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. Ephrin-B2 also binds EphA4, EphB1, EphB2, EphB3 and EphB4. Ephrin-B2 can be detected on monocytes, mesangial cells, CD34+ stem cells, bone marrow fibroblasts, activated melanocytes and melanoma cells, and pre-artery endothelial cells.Synonyms: EFNB2, EPH-related receptor tyrosine kinase ligand 5, EPLG5, HTK ligand, HTK-L, HTKL, LERK-5, LERK5
    ID gène
    1948
    NCBI Accession
    NP_004084
    UniProt
    P52799
    Pathways
    Signalisation RTK, Regulation of Muscle Cell Differentiation
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