EIF3I anticorps (AA 1-323) (HRP)

N° du produit ABIN1992223

Détail du produit anti-EIF3I anticorps (HRP)

Antigène: EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))

Épitope: AA 1-323

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3I est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Eukaryotic translation initiation factor 3 subunit I protein (1-323AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EIF3I

Antigène: EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))

Autre désignation: EIF3I (EIF3I Produits)

Synonymes: anticorps EIF3S2, anticorps PRO2242, anticorps TRIP-1, anticorps TRIP1, anticorps eIF3-beta, anticorps eIF3-p36, anticorps 36kDa, anticorps D4Ertd632e, anticorps Eif3s2, anticorps Trip1, anticorps eIF-3-beta, anticorps eIF3 p36, anticorps eif3s2, anticorps hm:zehn0464, anticorps wu:fb62b08, anticorps zgc:56211, anticorps zgc:77823, anticorps CaO19.2967, anticorps eIF-3 39 kDa subunit homolog, anticorps eIF3i, anticorps eif3-beta, anticorps eif3-p36, anticorps eif3i, anticorps pro2242, anticorps trip-1, anticorps trip1, anticorps eukaryotic translation initiation factor 3 subunit I, anticorps eukaryotic translation initiation factor 3, subunit I, anticorps Eukaryotic Initiation Factor, anticorps Eukaryotic translation initiation factor 3 subunit I, anticorps translation initiation factor eIF3 subunit i, anticorps eukaryotic translation initiation factor 3 subunit I L homeolog, anticorps EIF3I, anticorps Eif3i, anticorps eif-3.I, anticorps eIF3i, anticorps eif3i, anticorps TIF34, anticorps eif3i.L

Sujet:

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).

Aliases: eIF-3-beta antibody, eIF3 beta antibody, eIF3 p36 antibody, eIF3-beta antibody, eIF3-p36 antibody, eIF3i antibody, EIF3I_HUMAN antibody, EIF3S2 antibody, EIF3S2, formerly antibody, Eukaryotic translation initiation factor 3 subunit 2 antibody, Eukaryotic translation initiation factor 3 subunit 2 beta antibody, Eukaryotic translation initiation factor 3 subunit I antibody, eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD antibody, eukaryotic translation initiation factor 3, subunit 2 beta, 36 kDa antibody, eukaryotic translation initiation factor 3, subunit 2, formerly antibody, eukaryotic translation initiation factor 3, subunit I antibody, Predicted protein of HQ2242 antibody, PRO2242 antibody, TGF beta receptor interacting protein 1 antibody, TGF-beta receptor-interacting protein 1 antibody, TGFbeta receptor interacting protein 1 antibody, TGFbeta receptor-interacting protein 1 antibody, TRIP 1 antibody, TRIP-1 antibody, TRIP1 antibody

UniProt: Q13347

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Ribonucleoprotein Complex Subunit Organization, Synthesis of DNA