Calmodulin 1 anticorps (AA 81-152)

N° du produit ABIN2172206

Détail du produit anti-Calmodulin 1 anticorps

Antigène: Calmodulin 1 (Calm1)

Épitope: AA 81-152

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calmodulin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody may detect CAMI, CAM2, CAM3

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Calmodulin

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Calmodulin 1

Antigène: Calmodulin 1 (Calm1)

Autre désignation: Calmodulin (Calm1 Produits)

Synonymes: anticorps AI256814, anticorps AI327027, anticorps AI461935, anticorps AL024000, anticorps CaM, anticorps Calm, anticorps CaMI, anticorps CALML2, anticorps CAMI, anticorps CPVT4, anticorps DD132, anticorps LQT14, anticorps PHKD, anticorps caM, anticorps calm1, anticorps calm2-a, anticorps calm2-b, anticorps calm2a, anticorps calml2, anticorps cami, anticorps dd132, anticorps 3909, anticorps CAM, anticorps CG8472, anticorps Cal, anticorps Cal49A, anticorps CalA, anticorps Cam1, anticorps D-CaM, anticorps DmCaM, anticorps DmCalm, anticorps Dmel\CG8472, anticorps anon-EST:Posey59, anticorps cam, anticorps dCaM, anticorps l(2)03909, anticorps l(2)3909, anticorps lincRNA.S2634, anticorps calmodulin 1, anticorps calmodulin 2, anticorps calmodulin 1 (phosphorylase kinase, delta) L homeolog, anticorps Calmodulin, anticorps Calm1, anticorps Calm2, anticorps CALM1, anticorps calm1.L, anticorps Cam

Sujet:

Synonyms: CALM 1, CALM 2, CALM 3, CALM, CALM1, CALM2, CALM3, CALML2, Calmodulin 1, Calmodulin1, CAM 1, CAM 2, CAM 3, CaM, CAM I, CAM1, CAM2, CAM3, CAMB, CAMC, CAMI, CAMIII, DD132, PHKD, Phosphorylase kinase delta, Phosphorylase kinase delta subunit, Calmodulin1, Calmodulin 1, Calmodulin-1, Calmodulin2, Calmodulin 2, Calmodulin-2, Calmodulin3, Calmodulin 3, Calmodulin-3.

Background: Calmodulin consists of two glycoproteins, 34 and 39 kDa, sometimes designated epithelial antigen, epithelial specific antigen, and epithelial glycoprotein. The glycoproteins are located on the cell membrane surface and in the cytoplasm of virtually all epithelial cells with the exception of most squamous epithelia, hepatocytes, renal proximal tubular cells, gastric parietal cells and myoepithelial cells. Epithelial Calmodulin is found in the large majority of adenocarcinomas of most sites (50-100 % in various studies, as well as neuroendocrine tumours, including small cell carcinoma. Renal cell carcinoma and hepatocellular carcinoma stain in about 30 % of the cases. Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin Ca(2+) complex are a number of protein kinases and phosphatases. Calmodulin has four functional calcium binding sites.

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling