IL1R1 anticorps (Interleukin 1 Receptor, Type I)

Details for Product anti-IL1R1 Antibody No. ABIN2191761
Antigène
  • CD121A
  • D2S1473
  • IL-1R-alpha
  • IL1R
  • IL1RA
  • P80
  • CD121a
  • CD121b
  • IL-iR
  • Il1r-1
  • interleukin 1 receptor type 1
  • interleukin 1 receptor, type I
  • IL1R1
  • Il1r1
Reactivité
Souris
165
87
51
2
2
2
2
1
1
1
1
Hôte
Rat
160
32
30
9
3
2
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp IL1R1 est non-conjugé
19
10
8
8
7
5
3
3
2
2
2
2
1
1
1
1
1
1
1
Application
Immunoassay (IA), Inhibition Assay (InhA), Immunoprecipitation (IP), Purification (Purif), Western Blotting (WB)
150
109
69
35
26
17
15
14
11
8
5
4
4
2
2
2
1
1
1
1
1
1
Options
Clone Reg21
Stérilité 0.2 μm filtered
Plasmids, Primers & others Plasmids, Primers & others IL1R1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation Interleukin-1 Receptor Type I (IL1R1 Antibody Extrait)
Sujet The monoclonal antibody binds to soluble mouse interleukin-1 receptor type I. The IL-1 system includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor.
Pathways Signalisation NF-kappaB, Carbohydrate Homeostasis, Cancer Immune Checkpoints
Indications d'application For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For neutralization of biological activity dilutions have to be made according to the amounts IL-1 RI to be inactivated. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.
Restrictions For Research Use only
Buffer PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
Date de péremption 12 months
Produit citée dans: Obermeier, Kojouharoff, Hans, Schölmerich, Gross, Falk: "Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice." dans: Clinical and experimental immunology, Vol. 116, Issue 2, pp. 238-45, 1999 (PubMed).

Background publications Stern, Pan, Hellmann, Parker, Mueller, Hulmes, Kilian, Chizzonite: "Purification of homogeneity and amino acid sequence analysis of a receptor protein for interleukin 1." dans: Archives of biochemistry and biophysics, Vol. 274, Issue 1, pp. 26-36, 1989 (PubMed).

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