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FABP3 anticorps (Biotin)

FABP3 Reactivité: Humain WB, IP, IA Hôte: Souris Monoclonal 66E2 Biotin
N° du produit ABIN2191881
  • Antigène Voir toutes FABP3 Anticorps
    FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))
    Reactivité
    • 104
    • 63
    • 40
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 96
    • 41
    • 1
    Souris
    Clonalité
    • 97
    • 41
    Monoclonal
    Conjugué
    • 64
    • 20
    • 12
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FABP3 est conjugé à/à la Biotin
    Application
    • 87
    • 46
    • 42
    • 18
    • 15
    • 14
    • 13
    • 13
    • 10
    • 9
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunoassay (IA)
    Réactivité croisée (Details)
    Cross reactivity: Rat H-FABP : Yes, Mouse H-FABP : Yes, Swine H-FABP : Yes, Human B-FABP Average (in ELISA) Human A-FABP : No, Human I-FABP : No, Human L-FABP : No
    Stérilité
    0.2 μm filtered
    Clone
    66E2
    Isotype
    IgG1
    Top Product
    Discover our top product FABP3 Anticorps primaire
  • Indications d'application
    For Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.. Positive Heart cells, or recombinant H-FABP control
    Restrictions
    For Research Use only
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
  • Zhen, Berna, Jin, Pritt, Watson, Ackermann, Hale: "Quantification of heart fatty acid binding protein as a biomarker for drug-induced cardiac and musculoskeletal necroses." dans: Proteomics. Clinical applications, Vol. 1, Issue 7, pp. 661-71, (2010) (PubMed).

    Zimmermann-Ivol, Burkhard, Le Floch-Rohr, Allard, Hochstrasser, Sanchez: "Fatty acid binding protein as a serum marker for the early diagnosis of stroke: a pilot study." dans: Molecular & cellular proteomics : MCP, Vol. 3, Issue 1, pp. 66-72, (2004) (PubMed).

    Pelsers, Hanhoff, Van der Voort, Arts, Peters, Ponds, Honig, Rudzinski, Spener, de Kruijk, Twijnstra, Hermens, Menheere, Glatz: "Brain- and heart-type fatty acid-binding proteins in the brain: tissue distribution and clinical utility." dans: Clinical chemistry, Vol. 50, Issue 9, pp. 1568-75, (2004) (PubMed).

    Guillaume, Zimmermann, Burkhard, Hochstrasser, Sanchez: "A potential cerebrospinal fluid and plasmatic marker for the diagnosis of Creutzfeldt-Jakob disease." dans: Proteomics, Vol. 3, Issue 8, pp. 1495-9, (2003) (PubMed).

    Roos, Eymann, Symannek, Duppenthaler, Wodzig, Pelsers, Glatz: "Monoclonal antibodies to human heart fatty acid-binding protein." dans: Journal of immunological methods, Vol. 183, Issue 1, pp. 149-53, (1995) (PubMed).

  • Antigène
    FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))
    Autre désignation
    Fatty Acid-Binding Protein, Heart (FABP3 Produits)
    Synonymes
    anticorps Fabph-1, anticorps Fabph-4, anticorps Fabph1, anticorps Fabph4, anticorps H-FABP, anticorps Mdgi, anticorps FABP11, anticorps M-FABP, anticorps MDGI, anticorps O-FABP, anticorps FABP, anticorps FABP-3, anticorps fabp3, anticorps fatty acid binding protein 3, anticorps fatty acid binding protein 3, muscle and heart, anticorps FABP3, anticorps Fabp3, anticorps fabp3
    Sujet
    The monoclonal antibody 66E2 recognizes human heart-type fatty acid-binding protein (H-FABP) of both natural and recombinant origin. The H-FABP protein is derived from the human FABP3 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. H-FABP is localized in the heart, skeletal and smooth muscle, mammary epithelial cells, aorta, distal tubules of the kidney, lung, brain, placenta, and ovary. It is also useful as marker for brain damage. Furthermore, this antibody is useful for the purification of H-FABP. Aliases Fatty acid-binding protein 3, FABP3, Muscle fatty acid-binding protein, Mammary-derived growth inhibitor Immunogen Purified human H-FABP
    Pathways
    Monocarboxylic Acid Catabolic Process
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