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P27 anticorps

Reactivité: Humain IP, ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN233757
$482.90
Plus frais de port $45.00 et $20.00 pour carboglace
100 μL
Destination: Etats-Unis
Envoi sous 1 à 2 jours ouvrables
  • Antigène
    P27
    Reactivité
    • 32
    • 15
    • 15
    • 4
    • 1
    Humain
    Hôte
    • 26
    • 7
    Lapin
    Clonalité
    • 26
    • 7
    Polyclonal
    Conjugué
    • 21
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Inconjugué
    Application
    • 17
    • 15
    • 10
    • 5
    • 5
    • 4
    • 4
    Immunoprecipitation (IP), ELISA, Western Blotting (WB)
    Attributs du produit
    Concentration Definition: by Refractometry
    Purification
    Antiserum
    Immunogène
    This antibody was prepared from whole rabbit serum produced by repeated immunizations with a full length recombinant human p27 protein.
    Immunogentype:Recombinant
  • Indications d'application
    This antibody is suitable for use in ELISA, immunoprecipitation, co-immunoprecipitation and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band at ~27 kDa in size corresponding to p27 by western blotting in the appropriate cell lysate or extract. Anti-p27 is suitable for the detection by immunoblot of human p27. No reactivity is observed with p27 from mouse. This antibody is suitable for immmunoprecipitation of in vitro translated protein and cell lysates (C212, 3T3-L1) and will co-precipitate associated proteins. Optimal titers for other applications should be determined by the researcher.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    80 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    P27
    Synonymes
    Kip1, p27, cyclin dependent kinase inhibitor 1B, CDKN1B
    Classe de substances
    Viral Protein
    Sujet
    P27 Kip is a cyclin-dependent kinase inhibitor that shares a limited similarity with CDK inhibitor CDKN1A/p21.  p27 binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.
    Synonyms: Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor p27 p27Kip1
    ID gène
    1027, 4757962
    UniProt
    P46527
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