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CAND2 anticorps (C-Term)

CAND2 Reactivité: Humain IP, WB Hôte: Lapin Polyclonal unconjugated
Pubmed (3 références)
N° du produit ABIN233781
$658.50
Plus frais de port $45.00 et $20.00 pour carboglace
100 μL
Destination: Etats-Unis
Envoi sous 1 à 2 jours ouvrables
  • Antigène Voir toutes CAND2 Anticorps
    CAND2 (Cullin-Associated and Neddylation-Dissociated 2 (CAND2))
    Épitope
    • 3
    • 1
    • 1
    • 1
    AA 1130-1143, C-Term
    Reactivité
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 9
    Lapin
    Clonalité
    • 9
    Polyclonal
    Application
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunoprecipitation (IP), Western Blotting (WB)
    Attributs du produit
    Concentration Definition: by Refractometry
    Purification
    Antiserum
    Immunogène
    This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1130-1143 of Human CAND2/TIP120B coupled to KLH.
  • Indications d'application
    This antibody reacts with human, rat  and mouse CAND2 by western blot and immunoprecipita-tion.  The antibody immunoprecipitates in vitro translated protein and protein from transfected cell lysates (using HeLa and NIH-3T3, and others).  Coimmunoprecipitation of related proteins has not been tested.  A 125.4 kDa band corresponding to human CAND2 is detected.  CAND2 is specifically expressed in muscle and heart tissue.  Researchers should determine optimal titers for other applications.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    85 mg/mL
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Cheng, Dai, Zhao: "AtCAND1, a HEAT-repeat protein that participates in auxin signaling in Arabidopsis." dans: Plant physiology, Vol. 135, Issue 2, pp. 1020-6, (2004) (PubMed).

    Feng, Shen, Sullivan, Rubio, Xiong, Sun, Deng: "Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation." dans: The Plant cell, Vol. 16, Issue 7, pp. 1870-82, (2004) (PubMed).

    Liu, Furukawa, Matsumoto, Xiong: "NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases." dans: Molecular cell, Vol. 10, Issue 6, pp. 1511-8, (2002) (PubMed).

  • Antigène
    CAND2 (Cullin-Associated and Neddylation-Dissociated 2 (CAND2))
    Autre désignation
    CAND2 (CAND2 Produits)
    Synonymes
    cand1, si:ch211-257f16.2, si:dkey-72g22.1, CAND2, TIP120B, Tp120b, 2210404G23Rik, mKIAA0667, Tip120B, cullin-associated and neddylation-dissociated 2 (putative), cullin associated and neddylation dissociated 2 (putative), cand2, CAND2, Cand2
    Sujet
    CAND2 is also known as TIP120B, and TATA-binding protein-interacting protein 120B.  While both CAND1 (TIP120A) and CAND2 (TIP120B) are TATA-binding proteins and form complexes with various nuclear proteins involved in the control of eukaryotic gene transcription, CAND2 (TIP120B) is expressed specifically in muscle and heart tissue.  This is contrary to the ubiquitous expression of CAND1 (TIP120A). TIP120 homologs exist in various higher eukaryotes including D. melanogaster, C. elegans, and A. thaliana. TIP120B is 60% identical in amino acid sequence to TIP120A.
    Synonyms: Cullin associated NEDD8 dissociated protein 2 antibody, p120 CAND2 antibody, TATA binding protein interacting protein 120B antibody, TBP interacting protein antibody, Tp120b antibody
    ID gène
    23066, 112420977
    UniProt
    O75155
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