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ANAPC11 anticorps (C-Term)

ANAPC11 Reactivité: Humain IP, WB Hôte: Lapin Polyclonal unconjugated
Pubmed (2 références)
N° du produit ABIN233784
$658.50
Plus frais de port $45.00 et $20.00 pour carboglace
100 μL
Destination: Etats-Unis
Envoi sous 1 à 2 jours ouvrables
  • Antigène Voir toutes ANAPC11 Anticorps
    ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))
    Épitope
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 76-84, C-Term
    Reactivité
    • 47
    • 6
    • 6
    Humain
    Hôte
    • 25
    • 16
    • 6
    Lapin
    Clonalité
    • 31
    • 16
    Polyclonal
    Conjugué
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ANAPC11 est non-conjugé
    Application
    • 28
    • 21
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunoprecipitation (IP), Western Blotting (WB)
    Attributs du produit
    Concentration Definition: by Refractometry
    Purification
    Antiserum
    Immunogène
    This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 76-84 of Human APC11 coupled to KLH.
  • Indications d'application
    This antibody reacts with human APC11 by western blot and immunoprecipitation.  The antibody immunoprecipitates in vitro translated protein and protein from overexpressing cell lysates (using HeLa and NIH-3T3, and others).  Coimmunoprecipitation of related proteins (APC2) does occur.  A 9.8 kDa band corresponding to human APC11 is detected. Most cell lines or tissues expressing APC11 can be used as a positive control.  Researchers should determine optimal titers for other applications.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    85 mg/mL
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Furukawa, Ohta, Xiong: "Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins." dans: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 15758-65, (2002) (PubMed).

    Ohta, Michel, Xiong: "Association with cullin partners protects ROC proteins from proteasome-dependent degradation." dans: Oncogene, Vol. 18, Issue 48, pp. 6758-66, (2000) (PubMed).

  • Antigène
    ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))
    Autre désignation
    Apc11 (ANAPC11 Produits)
    Synonymes
    APC11, Apc11p, anapc11, RGD1561880, DDBDRAFT_0187183, DDBDRAFT_0231277, DDB_0187183, DDB_0231277, 1110011I19Rik, R75218, zgc:153671, si:dkey-237i9.4, anaphase promoting complex subunit 11, anaphase promoting complex subunit 11 L homeolog, anaphase-promoting complex subunit Apc11, ubiquitin-protein ligase Anaphase Promoting Complex, hypothetical protein, predicted protein, anaphase-promoting complex subunit 11, APC11 anaphase promoting complex subunit 11 homolog (yeast), ANAPC11, anapc11.L, anapc11, Anapc11, APC11, apc11, CAALFM_CR10610CA, LOC9320604, LOC692923
    Sujet
    APC11 is also known as Anaphase promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma associated RING finger protein, and HSPC214.  APC11 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC11 may function to recruit the E2 ubiquitin-conjugating enzymes to the complex.  APC11 interacts with the cullin domain of ANAPC2 and also interacts with UBE2D2.  APC11 shows both a cytoplasmic and nuclear localization.  APC11 is expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte.  APC11 is a member of the RING-type zinc finger family and is auto-ubiquitinylated.
    Synonyms: Anaphase promoting complex subunit 11 homolog antibody, APC11 anaphase promoting complex subunit 11 homolog antibody, Cyclosome subunit 11 antibody Hepatocellular carcinoma associated RING finger protein antibody HSPC 214 antibody
    ID gène
    51529, 19924286
    UniProt
    Q9NYG5
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