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CDC20 anticorps (C-Term)

CDC20 Reactivité: Humain IP, WB Hôte: Lapin Polyclonal unconjugated
Pubmed (1 reference)
N° du produit ABIN233786
$614.60
Plus frais de port $45.00 et $20.00 pour carboglace
100 μL
Destination: Etats-Unis
Envoi sous 1 à 2 jours ouvrables
  • Antigène Voir toutes CDC20 Anticorps
    CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))
    Épitope
    • 12
    • 9
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 486-499, C-Term
    Reactivité
    • 65
    • 22
    • 20
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 47
    • 19
    Lapin
    Clonalité
    • 46
    • 20
    Polyclonal
    Conjugué
    • 36
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CDC20 est non-conjugé
    Application
    • 42
    • 30
    • 24
    • 19
    • 16
    • 14
    • 6
    • 5
    • 2
    • 2
    • 1
    Immunoprecipitation (IP), Western Blotting (WB)
    Attributs du produit
    Concentration Definition: by Refractometry
    Purification
    Antiserum
    Immunogène
    This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 486-499 of Human CDC20 (fizzy) coupled to KLH.
  • Indications d'application
    This antibody reacts with human CDC20 (fizzy) by western blot and immunoprecipitation.  The antibody immunoprecipitates in vitro translated protein and protein from overexpressing cell lysates (using HeLa and NIH-3T3, and others).  Coimmunoprecipitation of related proteins has not been determined. A 54.7 kDa band corresponding to human CDC20 (fizzy) is detected. Most cell lines or tissues expressing CDC20 can be used as a positive control.  Researchers should determine optimal titers for other applications.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    85 mg/mL
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Yamamuro, Kano, Naito: "Functions of FZR1 and CDC20, activators of the anaphase-promoting complex, during meiotic maturation of swine oocytes." dans: Biology of reproduction, Vol. 79, Issue 6, pp. 1202-9, (2009) (PubMed).

  • Antigène
    CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))
    Autre désignation
    Cdc20 (CDC20 Produits)
    Synonymes
    X-FZY, ba276h19.3, cdc20a, fizzy1, p55cdc, CDC20A, bA276H19.3, p55CDC, 2310042N09Rik, C87100, cell division cycle 20, cell division cycle 20 L homeolog, cell division cycle 20 homolog (S. cerevisiae), cdc20, CDC20, cdc20.L, Cdc20
    Sujet
    CDC20, also known as fizzy, Cell division cycle protein 20 homolog, and p55CDC is required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. CDC20 is regulated by MAD2L1. In metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates.  The phosphorylated form of CDC20 interacts with APC/C. Synthesis is initiated at G1/S, protein level peaks in M phase and protein is abruptly degraded at M/G1 transition.
    Synonyms: CDC20 cell division cycle 20 homolog antibody, CDC20A antibody, Cell division cycle 20 antibody, Cell division cycle 20 homolog antibody, Cell division cycle protein 20 homolog antibody, fizzy antibody, MGC102824 antibody, p55CDC antibody
    ID gène
    991, 118402582
    UniProt
    Q12834
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