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NCOA3 anticorps

NCOA3 Reactivité: Humain ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN233839
$658.50
Plus frais de port $45.00 et $20.00 pour carboglace
Destination: Etats-Unis
Envoi sous 1 à 2 jours ouvrables
  • Antigène Voir toutes NCOA3 Anticorps
    NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))
    Reactivité
    • 70
    • 18
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 58
    • 12
    • 2
    • 1
    Lapin
    Clonalité
    • 62
    • 11
    Polyclonal
    Conjugué
    • 40
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NCOA3 est non-conjugé
    Application
    • 43
    • 28
    • 15
    • 13
    • 13
    • 9
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Specificité
    This product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with several isoforms of human NCOA3 protein (a, b, d, e and f).  A BLAST analysis was used to suggest cross-reactivity with NCOA3 from human and macaque sources based on a 100% homology with the immunizing sequence.  Expect partial reactivity with NCOA3 from dog, bovine, mouse and rat sources based on partial sequence homology.  Cross-reactivity with NCOA3 from other sources has not been determined.
    Attributs du produit
    This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. The NCOA3 (also known as nuclear receptor coactivator 3 isoform a) is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions in a hormone-dependent fashion. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. NCOA3 probably acts via remodeling of chromatin and is involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs),
    Purification
    affinity purified
    Stérilité
    Sterile filtered
    Immunogène
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human NCOA3 isoform a protein.
    Immunogen Type: Peptide
    Isotype
    IgG
  • Indications d'application
    This affinity purified antibody has been tested for use in ELISA and western blotting.
    Commentaires

    Gene Name: NCOA3

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.82 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.
    Date de péremption
    3 months
  • Antigène
    NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))
    Autre désignation
    NCOA3 (NCOA3 Produits)
    Synonymes
    NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP, 2010305B15Rik, AW321064, Actr, Aib1, Rac3, Src3, Tram-1, Tram1, p/Cip, pCip, actr, aib-1, aib1, cagh16, ctg26, kat13b, pcip, rac3, src-3, src3, tnrc14, tnrc16, tram-1, xSRC-3, nuclear receptor coactivator 3, nuclear receptor coactivator 3 S homeolog, NCOA3, Ncoa3, ncoa3.S
    Sujet
    This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. The NCOA3 (also known as nuclear receptor coactivator 3 isoform a) is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions in a hormone-dependent fashion. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. NCOA3 probably acts via remodeling of chromatin and is involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs),
    Synonyms: Nuclear receptor coactivator 3 NCoA-3 Thyroid hormone receptor activator molecule 1 TRAM-1, pCIP, bHLHe42 Receptor-associated coactivator 3, RAC-3 Amplified in breast cancer 1 protein, AIB-1 Steroid receptor coactivator protein 3, SRC-3
    ID gène
    8202, 32307126
    UniProt
    Q9Y6Q9
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha
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