ARAP1 anticorps (AA 1190-1450)

N° du produit ABIN238383

Détail du produit anti-ARAP1 anticorps

Antigène: ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))

Épitope: AA 1190-1450

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ARAP1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Specificité: The antibody ARAP1-2 reacts with C-terminal part of ARAP1, a 160 kDa adaptor protein.

Attributs du produit: Synonyms: KIAA0782, Centaurin-delta-2, Arf-GAP, Rho-GAP domain, ANK repeat and PHdomain-containing protein 1

Purification: Protein A affinity chromatography

Immunogène: His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1

Clone: ARAP1-2

Isotype: IgG1

Information d'application

Indications d'application: Suitable for Western Blotting (2 μg/mL). Immunoprecipitation. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 with 15 mM sodium azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze/thaw cycles.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur ARAP1

Antigène: ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))

Autre désignation: ARAP1 / CENTD2 (ARAP1 Produits)

Synonymes: anticorps CENTD2, anticorps ARAP1, anticorps Ci-ArfGAP-8, anticorps 2410002L19Rik, anticorps Centd2, anticorps mKIAA0782, anticorps ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1, anticorps centaurin, delta 2, anticorps ARAP1, anticorps centd2, anticorps Arap1

Sujet: ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.Synonyms: ANK repeat and PH domain-containing protein 1, Arf-GAP, Centaurin-delta-2, KIAA0782, Rho-GAP domain

ID gène: 116985

UniProt: Q96P48